Longitudinal Multi-Parametric Liquid Biopsy Approach Identifies Unique Features of Circulating Tumor Cell, Extracellular Vesicle, and Cell-Free DNA Characterization for Disease Mon...

by Corinna Keup, Vinay Suryaprakash, Markus Storbeck, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2021-01-01

LOH at 6q and 10q in fractionated circulating DNA of ovarian cancer patients is predictive for tumor cell spread and overall survival

by Kuhlmann Jan, Schwarzenbach Heidi, Wimberger Pauline, Poetsch Micaela, Kimmig Rainer, Kasimir-Bauer Sabine
Published 2012-07-01

Circulating Tumor Cells Expressing the Prostate Specific Membrane Antigen (PSMA) Indicate Worse Outcome in Primary, Non-Metastatic Triple-Negative Breast Cancer

by Sabine Kasimir-Bauer, Corinna Keup, Oliver Hoffmann, Siegfried Hauch, Rainer Kimmig, Ann-Kathrin Bittner
Published 2020-09-01

Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression

by Kasimir-Bauer Sabine, Rack Brigitte, Müller Volkmar, Pantel Klaus, Roth Carina, Janni Wolfgang, Schwarzenbach Heidi
Published 2011-01-01

Soluble Programmed Death Receptor Ligands sPD-L1 and sPD-L2 as Liquid Biopsy Markers for Prognosis and Platinum Response in Epithelial Ovarian Cancer

by Paul Buderath, Esther Schwich, Christina Jensen, Peter A. Horn, Rainer Kimmig, Sabine Kasimir-Bauer, Vera Rebmann
Published 2019-10-01

Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Can...

by Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2020-04-01

Digital Immune-Related Gene Expression Signatures In High-Grade Serous Ovarian Carcinoma: Developing Prediction Models For Platinum Response

by Mairinger F, Bankfalvi A, Schmid KW, Mairinger E, Mach P, Walter RFH, Borchert S, Kasimir-Bauer S, Kimmig R, Buderath P
Published 2019-11-01

Vesicular-Bound HLA-G as a Predictive Marker for Disease Progression in Epithelial Ovarian Cancer

by Esther Schwich, Vera Rebmann, Peter A. Horn, Alexander A. Celik, Christina Bade-Döding, Rainer Kimmig, Sabine Kasimir-Bauer, Paul Buderath
Published 2019-08-01

Dissimilar patterns of tumor-infiltrating immune cells at the invasive tumor front and tumor center are associated with response to neoadjuvant chemotherapy in primary breast cance...

by Lisa König, Fabian D. Mairinger, Oliver Hoffmann, Ann-Kathrin Bittner, Kurt W. Schmid, Rainer Kimmig, Sabine Kasimir-Bauer, Agnes Bankfalvi
Published 2019-02-01

Image-Based Identification and Genomic Analysis of Single Circulating Tumor Cells in High Grade Serous Ovarian Cancer Patients

by Carolin Salmon, Janina Levermann, Rui P. L. Neves, Sven-Thorsten Liffers, Jan Dominik Kuhlmann, Paul Buderath, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2021-07-01

Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer

by Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Mitra Tewes, Pawel Mach, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2019-02-01

Elevated levels of extracellular vesicles are associated with therapy failure and disease progression in breast cancer patients undergoing neoadjuvant chemotherapy

by Lisa König, Sabine Kasimir-Bauer, Ann-Kathrin Bittner, Oliver Hoffmann, Bettina Wagner, Luis Felipe Santos Manvailer, Rainer Kimmig, Peter A. Horn, Vera Rebmann
Published 2018-01-01

Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer

by Corinna Keup, Vinay Suryaprakash, Siegfried Hauch, Markus Storbeck, Peter Hahn, Markus Sprenger-Haussels, Hans-Christian Kolberg, Mitra Tewes, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2021-05-01

CXCR4 and JUNB double-positive disseminated tumor cells are detected frequently in breast cancer patients at primary diagnosis

by Galatea Kallergi, Oliver Hoffmann, Ann-Kathrin Bittner, Lina Papadimitriou, Spyridoula D. Katsarou, Nefeli Zacharopoulou, Michalis Zervakis, Stelios Sfakianakis, Christos Stournaras, Vassilis Georgoulias, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2020-04-01

Elevated serum RAS p21 is an independent prognostic factor in metastatic breast cancer

by Malgorzata Banys-Paluchowski, Tanja Fehm, Wolfgang Janni, Bahriye Aktas, Peter A. Fasching, Sabine Kasimir-Bauer, Karin Milde-Langosch, Klaus Pantel, Brigitte Rack, Sabine Riethdorf, Erich-Franz Solomayer, Isabell Witzel, Volkmar Müller
Published 2018-05-01

Definition and Independent Validation of a Proteomic-Classifier in Ovarian Cancer

by Sabine Kasimir-Bauer, Joanna Roder, Eva Obermayr, Sven Mahner, Ignace Vergote, Liselore Loverix, Elena Braicu, Jalid Sehouli, Nicole Concin, Rainer Kimmig, Lelia Net, Heinrich Roder, Robert Zeillinger, Stefanie Aust, on behalf of the OVCAD (Ovarian Cancer Diagnosis initiative)
Published 2020-09-01