The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression.

by Anna Coulibaly, Astrid Haas, Simone Steinmann, Anke Jakobs, Thomas J Schmidt, Karl-Heinz Klempnauer
Published 2018-01-01

PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines.

by Gundula Streubel, Caroline Bouchard, Hannah Berberich, Marc S Zeller, Sophia Teichmann, Jürgen Adamkiewicz, Rolf Müller, Karl-Heinz Klempnauer, Uta-Maria Bauer
Published 2013-01-01

Interaction of the transactivation domain of B-Myb with the TAZ2 domain of the coactivator p300: molecular features and properties of the complex.

by Ojore Oka, Lorna C Waters, Sarah L Strong, Nuvjeevan S Dosanjh, Vaclav Veverka, Frederick W Muskett, Philip S Renshaw, Karl-Heinz Klempnauer, Mark D Carr
Published 2012-01-01