Genome engineering with TALE and CRISPR systems in neuroscience

by Han B Lee, Brynn N Sundberg, Ashley N Sigafoos, Karl J Clark, Karl J Clark
Published 2016-04-01

High efficiency In Vivo genome engineering with a simplified 15-RVD GoldyTALEN design.

by Alvin C Ma, Han B Lee, Karl J Clark, Stephen C Ekker
Published 2013-01-01

The endocannabinoid gene faah2a modulates stress-associated behavior in zebrafish.

by Randall G Krug, Han B Lee, Louis Y El Khoury, Ashley N Sigafoos, Morgan O Petersen, Karl J Clark
Published 2018-01-01

An in vivo method to quantify lymphangiogenesis in zebrafish.

by Scott J Hoffman, Peter J Psaltis, Karl J Clark, Daniel B Spoon, Colin D Chue, Stephen C Ekker, Robert D Simari
Published 2012-01-01

Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration

by Maira P. Almeida, Jordan M. Welker, Sahiba Siddiqui, Jon Luiken, Stephen C. Ekker, Karl J. Clark, Jeffrey J. Essner, Maura McGrail
Published 2021-01-01

Disruption of pdgfra alters endocardial and myocardial fusion during zebrafish cardiac assembly

by Suzan El-Rass, Shahram Eisa-Beygi, Edbert Khong, Koroboshka Brand-Arzamendi, Antonio Mauro, Haibo Zhang, Karl J. Clark, Stephen C. Ekker, Xiao-Yan Wen
Published 2017-03-01

Robust activation of microhomology-mediated end joining for precision gene editing applications.

by Hirotaka Ata, Thomas L Ekstrom, Gabriel Martínez-Gálvez, Carla M Mann, Alexey V Dvornikov, Kyle J Schaefbauer, Alvin C Ma, Drena Dobbs, Karl J Clark, Stephen C Ekker
Published 2018-09-01

Haploinsufficiency as a disease mechanism in GNB1‐associated neurodevelopmental disorder

by Laura Schultz‐Rogers, Ikuo Masuho, Filippo Pinto e Vairo, Christopher T. Schmitz, Tanya L. Schwab, Karl J. Clark, Lauren Gunderson, Pavel N. Pichurin, Klaas Wierenga, Kirill A. Martemyanov, Eric W. Klee
Published 2020-11-01

Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fo...

by Stephanie E Westcot, Julia Hatzold, Mark D Urban, Stefânia K Richetti, Kimberly J Skuster, Rhianna M Harm, Roberto Lopez Cervera, Noriko Umemoto, Melissa S McNulty, Karl J Clark, Matthias Hammerschmidt, Stephen C Ekker
Published 2015-01-01

Development and Application of Bovine and Porcine Oligonucleotide Arrays with Protein-Based Annotation

by John R. Garbe, Christine G. Elsik, Eric Antoniou, James M. Reecy, Karl J. Clark, Anand Venkatraman, Jae-Woo Kim, Robert D. Schnabel, C. Michael Dickens, Russell D. Wolfinger, Scott C. Fahrenkrug, Jeremy F. Taylor
Published 2010-01-01

Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord

by Craig M. Nelson, Craig M. Nelson, Vanda A. Lennon, Vanda A. Lennon, Vanda A. Lennon, Han Lee, Randall G. Krug, Aichurok Kamalova, Nicolas N. Madigan, Karl J. Clark, Anthony J. Windebank, John R. Henley, John R. Henley
Published 2019-04-01

Efficient targeted integration directed by short homology in zebrafish and mammalian cells

by Wesley A Wierson, Jordan M Welker, Maira P Almeida, Carla M Mann, Dennis A Webster, Melanie E Torrie, Trevor J Weiss, Sekhar Kambakam, Macy K Vollbrecht, Merrina Lan, Kenna C McKeighan, Jacklyn Levey, Zhitao Ming, Alec Wehmeier, Christopher S Mikelson, Jeffrey A Haltom, Kristen M Kwan, Chi-Bin Chien, Darius Balciunas, Stephen C Ekker, Karl J Clark, Beau R Webber, Branden S Moriarity, Stacy L Solin, Daniel F Carlson, Drena L Dobbs, Maura McGrail, Jeffrey Essner
Published 2020-05-01

Building the vertebrate codex using the gene breaking protein trap library

by Noriko Ichino, MaKayla R Serres, Rhianna M Urban, Mark D Urban, Anthony J Treichel, Kyle J Schaefbauer, Lauren E Greif, Gaurav K Varshney, Kimberly J Skuster, Melissa S McNulty, Camden L Daby, Ying Wang, Hsin-kai Liao, Suzan El-Rass, Yonghe Ding, Weibin Liu, Jennifer L Anderson, Mark D Wishman, Ankit Sabharwal, Lisa A Schimmenti, Sridhar Sivasubbu, Darius Balciunas, Matthias Hammerschmidt, Steven Arthur Farber, Xiao-Yan Wen, Xiaolei Xu, Maura McGrail, Jeffrey J Essner, Shawn M Burgess, Karl J Clark, Stephen C Ekker
Published 2020-08-01