Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain

by Nalin Singh, Bogdan Barnych, Karen M. Wagner, Debin Wan, Christophe Morisseau, Bruce D. Hammock
Published 2021-03-01

Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors

by Sean D. Kodani, Debin Wan, Karen M. Wagner, Sung Hee Hwang, Christophe Morisseau, Bruce D. Hammock
Published 2018-10-01

In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea

by Debin Wan, Jun Yang, Cindy B. McReynolds, Bogdan Barnych, Karen M. Wagner, Christophe Morisseau, Sung Hee Hwang, Jia Sun, Jia Sun, René Blöcher, Bruce D. Hammock
Published 2019-05-01

Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures.

by Bora Inceoglu, Dorota Zolkowska, Hyun Ju Yoo, Karen M Wagner, Jun Yang, Edward Hackett, Sung Hee Hwang, Kin Sing Stephen Lee, Michael A Rogawski, Christophe Morisseau, Bruce D Hammock
Published 2013-01-01