661W is a retinal ganglion precursor-like cell line in which glaucoma-associated optineurin mutants induce cell death selectively

by Zuberwasim Sayyad, Kapil Sirohi, Vegesna Radha, Ghanshyam Swarup
Published 2017-12-01

A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin.

by Kapil Sirohi, Asha Kumari, Vegesna Radha, Ghanshyam Swarup
Published 2015-01-01

Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases.

by Anand Sripada, Kapil Sirohi, Lidia Michalec, Lei Guo, Jerome T McKay, Sangya Yadav, Mukesh Verma, James Good, Donald Rollins, Magdalena M Gorska, Rafeul Alam
Published 2021-03-01