Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P2RX7 purinoceptor antagonism

by Rasha Al-Khalidi, Chiara Panicucci, Paul Cox, Natalia Chira, Justyna Róg, Christopher N. J. Young, Rhiannon E. McGeehan, Kameshwari Ambati, Jayakrishna Ambati, Krzysztof Zabłocki, Elisabetta Gazzerro, Stephen Arkle, Claudio Bruno, Dariusz C. Górecki
Published 2018-04-01

Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration

by Siddharth Narendran, Felipe Pereira, Praveen Yerramothu, Ivana Apicella, Shao-bin Wang, Kameshwari Ambati, Shuichiro Hirahara, Younghee Kim, Meenakshi Ambati, Vidya L. Ambati, Peirong Huang, Akhil Varshney, Yosuke Nagasaka, Shinichi Fukuda, Kirstie L. Baker, Kenneth M. Marion, Jan M. Deussing, Srinivas R. Sadda, Bradley D. Gelfand, Jayakrishna Ambati
Published 2021-04-01

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development

by Jayakrishna Ambati, Joseph Magagnoli, Hannah Leung, Shao-bin Wang, Chris A. Andrews, Dongxu Fu, Akshat Pandey, Srabani Sahu, Siddharth Narendran, Shuichiro Hirahara, Shinichi Fukuda, Jian Sun, Lekha Pandya, Meenakshi Ambati, Felipe Pereira, Akhil Varshney, Tammy Cummings, James W. Hardin, Babatunde Edun, Charles L. Bennett, Kameshwari Ambati, Benjamin J. Fowler, Nagaraj Kerur, Christian Röver, Norbert Leitinger, Brian C. Werner, Joshua D. Stein, S. Scott Sutton, Bradley D. Gelfand
Published 2020-09-01