Chemotherapy‐Enriched THBS2‐Deficient Cancer Stem Cells Drive Hepatocarcinogenesis through Matrix Softness Induced Histone H3 Modifications

by Kai‐Yu Ng, Queenie T. Shea, Tin‐Lok Wong, Steve T. Luk, Man Tong, Chung‐Mau Lo, Kwan Man, Jing‐Ping Yun, Xin‐Yuan Guan, Terence K. Lee, Yong‐Ping Zheng, Stephanie Ma
Published 2021-03-01

Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

by Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Published 2016-05-01

ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma

by Man Tong, Tsun-Ming Fung, Steve T. Luk, Kai-Yu Ng, Terence K. Lee, Chi-Ho Lin, Judy W. Yam, Kwok Wah Chan, Fai Ng, Bo-Jian Zheng, Yun-Fei Yuan, Dan Xie, Chung-Mau Lo, Kwan Man, Xin-Yuan Guan, Stephanie Ma
Published 2015-07-01

PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation

by Lok Hei Chan, Lei Zhou, Kai Yu Ng, Tin Lok Wong, Terence K. Lee, Rakesh Sharma, Jane H. Loong, Yick Pang Ching, Yun-Fei Yuan, Dan Xie, Chung Mau Lo, Kwan Man, Benedetta Artegiani, Hans Clevers, Helen H. Yan, Suet Yi Leung, Stéphane Richard, Xin-Yuan Guan, Michael S.Y. Huen, Stephanie Ma
Published 2018-10-01