Unraveling Heterogeneity in Epithelial Cell Fates of the Mammary Gland and Breast Cancer

by Alexandr Samocha, Hanna Doh, Kai Kessenbrock, Jeroen P. Roose
Published 2019-09-01

Experimental Considerations for Single-Cell RNA Sequencing Approaches

by Quy H. Nguyen, Nicholas Pervolarakis, Kevin Nee, Kai Kessenbrock
Published 2018-09-01

Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release

by Virginia Egea, Kai Kessenbrock, Devon Lawson, Alexander Bartelt, Christian Weber, Christian Ries
Published 2021-05-01

Microfluidic platform accelerates tissue processing into single cells for molecular analysis and primary culture models

by Jeremy A. Lombardo, Marzieh Aliaghaei, Quy H. Nguyen, Kai Kessenbrock, Jered B. Haun
Published 2021-05-01

Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity

by Nicholas Pervolarakis, Quy H. Nguyen, Justice Williams, Yanwen Gong, Guadalupe Gutierrez, Peng Sun, Darisha Jhutty, Grace X.Y. Zheng, Corey M. Nemec, Xing Dai, Kazuhide Watanabe, Kai Kessenbrock
Published 2020-10-01

Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics

by Daniel Haensel, Suoqin Jin, Peng Sun, Rachel Cinco, Morgan Dragan, Quy Nguyen, Zixuan Cang, Yanwen Gong, Remy Vu, Adam L. MacLean, Kai Kessenbrock, Enrico Gratton, Qing Nie, Xing Dai
Published 2020-03-01

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

by Christian F. Guerrero-Juarez, Priya H. Dedhia, Suoqin Jin, Rolando Ruiz-Vega, Dennis Ma, Yuchen Liu, Kosuke Yamaga, Olga Shestova, Denise L. Gay, Zaixin Yang, Kai Kessenbrock, Qing Nie, Warren S. Pear, George Cotsarelis, Maksim V. Plikus
Published 2019-02-01

Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation

by M. Rezaa Mohammadi, Samuel Mathew Rodriguez, Jennifer Cam Luong, Shiri Li, Rui Cao, Hamad Alshetaiwi, Hien Lau, Hayk Davtyan, Mathew Blurton Jones, Mahtab Jafari, Kai Kessenbrock, S. Armando Villalta, Paul de Vos, Weian Zhao, Jonathan R. T. Lakey
Published 2021-06-01

Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity

by Quy H. Nguyen, Nicholas Pervolarakis, Kerrigan Blake, Dennis Ma, Ryan Tevia Davis, Nathan James, Anh T. Phung, Elizabeth Willey, Raj Kumar, Eric Jabart, Ian Driver, Jason Rock, Andrei Goga, Seema A. Khan, Devon A. Lawson, Zena Werb, Kai Kessenbrock
Published 2018-05-01