AF-6 Protects Against Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson’s Disease

by Adeline H. Basil, Joan P. L. Sim, Grace G. Y. Lim, Shuping Lin, Hui Ying Chan, Hui Ying Chan, Simone Engelender, Kah-Leong Lim, Kah-Leong Lim, Kah-Leong Lim, Kah-Leong Lim
Published 2017-08-01

Animal Models of Parkinson's Disease 2012

by Yuzuru Imai, Katerina Venderova, Kah-Leong Lim
Published 2012-01-01

K63-linked ubiquitination and neurodegeneration

by Kah-Leong Lim, Grace G.Y. Lim
Published 2011-07-01

Mitochondrial homeostasis in Parkinson's disease - a triumvirate rule?

by Chee-Hoe Ng, Liting Hang, Kah-Leong Lim
Published 2017-01-01

Mitochondrial Dysfunction and Parkinson’s Disease—Near-Infrared Photobiomodulation as a Potential Therapeutic Strategy

by Aaron Song Chuan Foo, Aaron Song Chuan Foo, Tuck Wah Soong, Tseng Tsai Yeo, Kah-Leong Lim, Kah-Leong Lim
Published 2020-04-01

Natural Molecules From Chinese Herbs Protecting Against Parkinson’s Disease via Anti-oxidative Stress

by Yaqi Ding, Chenqi Xin, Cheng-Wu Zhang, Kah-Leong Lim, Kah-Leong Lim, Hang Zhang, ZhenQian Fu, Lin Li, Wei Huang
Published 2018-08-01

The Sources of Reactive Oxygen Species and Its Possible Role in the Pathogenesis of Parkinson’s Disease

by Minrui Weng, Xiaoji Xie, Chao Liu, Kah-Leong Lim, Cheng-wu Zhang, Lin Li
Published 2018-01-01

Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination.

by Katherine C M Chew, Noriyuki Matsuda, Keiko Saisho, Grace G Y Lim, Chou Chai, Hui-Mei Tan, Keiji Tanaka, Kah-Leong Lim
Published 2011-01-01

Proteasome inhibition promotes Parkin-Ubc13 interaction and lysine 63-linked ubiquitination.

by Grace G Y Lim, Katherine C M Chew, Xiao-Hui Ng, Adeline Henry-Basil, Roy W X Sim, Jeanne M M Tan, Chou Chai, Kah-Leong Lim
Published 2013-01-01

MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity

by Bobby Thomas, Rainer von Coelln, Allen S. Mandir, Daniel B. Trinkaus, Mohamed H. Farah, Kah Leong Lim, Noel Y. Calingasan, M. Flint Beal, Valina L. Dawson, Ted M. Dawson
Published 2007-05-01

Static Magnetic Field Stimulation Enhances Oligodendrocyte Differentiation and Secretion of Neurotrophic Factors

by Ankshita Prasad, Daniel B. Loong Teh, Agata Blasiak, Chou Chai, Yang Wu, Payam M. Gharibani, In Hong Yang, Thang T. Phan, Kah Leong Lim, Hyunsoo Yang, Xiaogang Liu, Angelo H. All
Published 2017-07-01

Discovery of indolylpiperazinylpyrimidines with dual-target profiles at adenosine A2A and dopamine D2 receptors for Parkinson's disease treatment.

by Yi-Ming Shao, Xiaohua Ma, Priyankar Paira, Aaron Tan, Deron Raymond Herr, Kah Leong Lim, Chee Hoe Ng, Gopalakrishnan Venkatesan, Karl-Norbert Klotz, Stephanie Federico, Giampiero Spalluto, Siew Lee Cheong, Yu Zong Chen, Giorgia Pastorin
Published 2018-01-01

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1

by Frederick C. Nucifora, Leslie G. Nucifora, Chee-Hoe Ng, Nicolas Arbez, Yajuan Guo, Elaine Roby, Vered Shani, Simone Engelender, Dong Wei, Xiao-Fang Wang, Tianxia Li, Darren J. Moore, Olga Pletnikova, Juan C. Troncoso, Akira Sawa, Ted M. Dawson, Wanli Smith, Kah-Leong Lim, Christopher A. Ross
Published 2016-06-01