Cinaciguat Prevents Postnatal Closure of Ductus Arteriosus by Vasodilation and Anti-remodeling in Neonatal Rats

by Yu-Chi Hung, Yu-Chi Hung, Yi-Ching Liu, Bin-Nan Wu, Bin-Nan Wu, Bin-Nan Wu, Jwu-Lai Yeh, Jwu-Lai Yeh, Jwu-Lai Yeh, Jwu-Lai Yeh, Jong-Hau Hsu, Jong-Hau Hsu
Published 2021-07-01

Role of Extracellular Matrix in Pathophysiology of Patent Ductus Arteriosus: Emphasis on Vascular Remodeling

by Ting-Yi Lin, Jwu-Lai Yeh, Jong-Hau Hsu
Published 2020-07-01

Molecular Mechanisms for Regulating Postnatal Ductus Arteriosus Closure

by Yu-Chi Hung, Jwu-Lai Yeh, Jong-Hau Hsu
Published 2018-06-01

Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca2+ sensitizatio...

by Chung-Pin Liu, Jwu-Lai Yeh, Shu-Fen Liou, Bin-Nan Wu, Ing-Jun Chen
Published 2016-02-01

KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways...

by Shu-Fen Liou, Jong-Hau Hsu, You-Ting Chen, Ing-Jun Chen, Jwu-Lai Yeh
Published 2015-06-01

Molecular Mechanisms Underlying Remodeling of Ductus Arteriosus: Looking Beyond the Prostaglandin Pathway

by Ho-Wei Hsu, Ting-Yi Lin, Yi-Ching Liu, Jwu-Lai Yeh, Jong-Hau Hsu
Published 2021-03-01

Vasculoprotective effects of Centella asiatica, Justicia gendarussa and Imperata cylindrica decoction via the NOXs-ROS-NF-κB pathway in spontaneously hypertensive rats

by Erna Sulistyowati, Ren-Long Jan, Shu-Fen Liou, Ying-Fu Chen, Bin-Nan Wu, Jong-Hau Hsu, Jwu-Lai Yeh
Published 2020-07-01

KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPARγ and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes

by Chung-Pin Liu, Pei-Chun Chau, Chain-Ting Chang, Li-Mei An, Jwu-Lai Yeh, Ing-Jun Chen, Bin-Nan Wu
Published 2018-09-01

In Vitro Evaluation of the Anti-Inflammatory Effect of KMUP-1 and In Vivo Analysis of Its Therapeutic Potential in Osteoarthritis

by Shang-En Huang, Erna Sulistyowati, Yu-Ying Chao, Bin-Nan Wu, Zen-Kong Dai, Jong-Hau Hsu, Jwu-Lai Yeh
Published 2021-05-01

Angiotensin-Converting Enzyme 2 Activator Ameliorates Severe Pulmonary Hypertension in a Rat Model of Left Pneumonectomy Combined With VEGF Inhibition

by I-Chen Chen, I-Chen Chen, I-Chen Chen, Jao-Yu Lin, Yi-Ching Liu, Chee-Yin Chai, Jwu-Lai Yeh, Jwu-Lai Yeh, Jong-Hau Hsu, Jong-Hau Hsu, Bin-Nan Wu, Bin-Nan Wu, Zen-Kong Dai, Zen-Kong Dai, Zen-Kong Dai
Published 2021-02-01

Evaluation of Tc-99m (V) DMSA Binding to Human Plasma Proteins

by Bi-Fang Lee, Jwu-Lai Yeh, Nan-Tsing Chiu, Gin-Chung Liu, Hsin-Su Yu, Mei-Hui Wang, Lie-Hang Shen
Published 2008-01-01

San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways

by Shu-Fen Liou, Hung-Jen Ke, Jong-Hau Hsu, Jyh-Chong Liang, Hung-Hong Lin, Ing-Jun Chen, Jwu-Lai Yeh
Published 2011-01-01

Endothelial nitric oxide synthase-enhancing G-protein coupled receptor antagonist inhibits pulmonary artery hypertension by endothelin-1-dependent and endothelin-1-independent path...

by Chung-Pin Liu, Zen-Kong Dai, Chein-Heng Huang, Jwu-Lai Yeh, Bin-Nan Wu, Jiunn-Ren Wu, Ing-Jun Chen
Published 2014-06-01

BK_Ca Channel Inhibition by Peripheral Nerve Injury Is Restored by the Xanthine Derivative KMUP-1 in Dorsal Root Ganglia

by Kuang-I Cheng, Kan-Ting Yang, Chien-Lun Kung, Yu-Chi Cheng, Jwu-Lai Yeh, Zen-Kong Dai, Bin-Nan Wu
Published 2021-04-01

KMUP-1 Ameliorates Ischemia-Induced Cardiomyocyte Apoptosis through the NO–cGMP–MAPK Signaling Pathways

by Meng-Luen Lee, Erna Sulistyowati, Jong-Hau Hsu, Bo-Yau Huang, Zen-Kong Dai, Bin-Nan Wu, Yu-Ying Chao, Jwu-Lai Yeh
Published 2019-04-01

Exogenous Heat Shock Cognate Protein 70 Suppresses LPS-Induced Inflammation by Down-Regulating NF-κB through MAPK and MMP-2/-9 Pathways in Macrophages

by Erna Sulistyowati, Mei-Yueh Lee, Lin-Chi Wu, Jong-Hau Hsu, Zen-Kong Dai, Bin-Nan Wu, Ming-Chung Lin, Jwu-Lai Yeh
Published 2018-08-01

ANTI-PROLIFERATIVE EFFECTIVENESS OF LERCANIDIPINE AND ITS MECHANISM OF ACTION (EXPERIMENTAL STUDY)

by Jiunn-Ren Wu, Shu-Fen Liou, Shin-Wha Lin, Chee-Yin Chai, Zen-Kong Dai, Jyh-Chong Liang, Ing-Jun Chen, Jwu-Lai Yeh
Published 2010-10-01

Extracellular heat shock protein HSC70 protects against lipopolysaccharide-induced hypertrophic responses in rat cardiomyocytes

by Ren-Long Jan, Shun-Cheng Yang, Yi-Ching Liu, Rei-Cheng Yang, Siao-Ping Tsai, Shang-En Huang, Jwu-Lai Yeh, Jong-Hau Hsu
Published 2020-08-01

KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways.

by Shu-Fen Liou, Jong-Hau Hsu, I-Ling Lin, Mei-Ling Ho, Pei-Chuan Hsu, Li-Wen Chen, Ing-Jun Chen, Jwu-Lai Yeh
Published 2013-01-01

The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D₃ Plus Nicotine

by Shu-Fen Liou, Thi Tuyet Ngan Nguyen, Jong-Hau Hsu, Erna Sulistyowati, Shang-En Huang, Bin-Nan Wu, Ming-Chung Lin, Jwu-Lai Yeh
Published 2020-10-01