Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves

by Rhys M Adams, Thierry Mora, Aleksandra M Walczak, Justin B Kinney
Published 2016-12-01

Mapping DNA sequence to transcription factor binding energy in vivo.

by Stephanie L Barnes, Nathan M Belliveau, William T Ireland, Justin B Kinney, Rob Phillips
Published 2019-02-01

Measuring cis-regulatory energetics in living cells using allelic manifolds

by Talitha L Forcier, Andalus Ayaz, Manraj S Gill, Daniel Jones, Rob Phillips, Justin B Kinney
Published 2018-12-01

Selection for Protein Stability Enriches for Epistatic Interactions

by Anna Posfai, Juannan Zhou, Joshua B. Plotkin, Justin B. Kinney, David M. McCandlish
Published 2018-08-01

Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.

by Jonathan J Ipsaro, Chen Shen, Eri Arai, Yali Xu, Justin B Kinney, Leemor Joshua-Tor, Christopher R Vakoc, Junwei Shi
Published 2017-01-01

The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

by Eric Wang, Shinpei Kawaoka, Jae-Seok Roe, Junwei Shi, Anja F Hohmann, Yali Xu, Anand S Bhagwat, Yutaka Suzuki, Justin B Kinney, Christopher R Vakoc
Published 2015-04-01

Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization

by Serif Senturk, Nitin H. Shirole, Dawid G. Nowak, Vincenzo Corbo, Debjani Pal, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Justin B. Kinney, Raffaella Sordella
Published 2017-02-01

Deciphering the regulatory genome of Escherichia coli, one hundred promoters at a time

by William T Ireland, Suzannah M Beeler, Emanuel Flores-Bautista, Nicholas S McCarty, Tom Röschinger, Nathan M Belliveau, Michael J Sweredoski, Annie Moradian, Justin B Kinney, Rob Phillips
Published 2020-09-01