Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Show Comparable Functionality to Their Autologous Origin

by Mark Jakob, Mario Hambrecht, Jennifer L. Spiegel, Julia Kitz, Martin Canis, Ralf Dressel, Katrin Streckfuss-Bömeke
Published 2021-12-01

Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer

by Hannah Flebbe, Feda H. Hamdan, Vijayalakshmi Kari, Julia Kitz, Jochen Gaedcke, B. Michael Ghadimi, Steven A. Johnsen, Marian Grade
Published 2019-08-01

Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma

by Friedrich Ihler, Ronja Gratz, Hendrik A. Wolff, Bernhard G. Weiss, Mattis Bertlich, Julia Kitz, Gabriela Salinas, Margret Rave-Fränk, Martin Canis
Published 2018-01-01

Prognostic Value of MicroRNAs in Preoperative Treated Rectal Cancer

by Azadeh Azizian, Ingo Epping, Frank Kramer, Peter Jo, Markus Bernhardt, Julia Kitz, Gabriela Salinas, Hendrik A. Wolff, Marian Grade, Tim Beißbarth, B. Michael Ghadimi, Jochen Gaedcke
Published 2016-04-01

KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer.

by Peter Jo, Markus Bernhardt, Manuel Nietert, Alexander König, Azadeh Azizian, Markus A Schirmer, Marian Grade, Julia Kitz, Kirsten Reuter-Jessen, Michael Ghadimi, Philipp Ströbel, Hans-Ulrich Schildhaus, Jochen Gaedcke
Published 2020-01-01

Heterogeneity of KRAS Mutation Status in Rectal Cancer.

by Peter Jo, Alexander König, Markus Schirmer, Julia Kitz, Lena-Christin Conradi, Azadeh Azizian, Markus Bernhardt, Hendrik A Wolff, Marian Grade, Michael Ghadimi, Philipp Ströbel, Hans-Ulrich Schildhaus, Jochen Gaedcke
Published 2016-01-01

KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer

by Peter Jo, Markus Bernhardt, Manuel Nietert, Alexander König, Azadeh Azizian, Markus A. Schirmer, Marian Grade, Julia Kitz, Kirsten Reuter-Jessen, Michael Ghadimi, Philipp Ströbel, Hans-Ulrich Schildhaus, Jochen Gaedcke, Sumitra Deb
Published 2020-01-01

The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness

by Vijayalakshmi Kari, Sanjay Kumar Raul, Jana Maria Henck, Julia Kitz, Frank Kramer, Robyn Laura Kosinsky, Nadine Übelmesser, Wael Yassin Mansour, Jessica Eggert, Melanie Spitzner, Zeynab Najafova, Holger Bastians, Marian Grade, Jochen Gaedcke, Florian Wegwitz, Steven A. Johnsen
Published 2019-01-01

EpCAM ectodomain EpEX is a ligand of EGFR that counteracts EGF-mediated epithelial-mesenchymal transition through modulation of phospho-ERK1/2 in head and neck cancers.

by Min Pan, Henrik Schinke, Elke Luxenburger, Gisela Kranz, Julius Shakhtour, Darko Libl, Yuanchi Huang, Aljaž Gaber, Miha Pavšič, Brigita Lenarčič, Julia Kitz, Mark Jakob, Sabina Schwenk-Zieger, Martin Canis, Julia Hess, Kristian Unger, Philipp Baumeister, Olivier Gires
Published 2018-09-01

Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolitesResearch in context

by Melanie S. Patzak, Vijayalakshmi Kari, Shilpa Patil, Feda H. Hamdan, Robert G. Goetze, Marius Brunner, Jochen Gaedcke, Julia Kitz, Duncan I. Jodrell, Frances M. Richards, Christian Pilarsky, Robert Gruetzmann, Petra Rümmele, Thomas Knösel, Elisabeth Hessmann, Volker Ellenrieder, Steven A. Johnsen, Albrecht Neesse
Published 2019-02-01

Comparative proteomics reveals a diagnostic signature for pulmonary head‐and‐neck cancer metastasis

by Hanibal Bohnenberger, Lars Kaderali, Philipp Ströbel, Diego Yepes, Uwe Plessmann, Neekesh V Dharia, Sha Yao, Carina Heydt, Sabine Merkelbach‐Bruse, Alexander Emmert, Jonatan Hoffmann, Julius Bodemeyer, Kirsten Reuter‐Jessen, Anna‐Maria Lois, Leif Hendrik Dröge, Philipp Baumeister, Christoph Walz, Lorenz Biggemann, Roland Walter, Björn Häupl, Federico Comoglio, Kuan‐Ting Pan, Sebastian Scheich, Christof Lenz, Stefan Küffer, Felix Bremmer, Julia Kitz, Maren Sitte, Tim Beißbarth, Marc Hinterthaner, Martin Sebastian, Joachim Lotz, Hans‐Ulrich Schildhaus, Hendrik Wolff, Bernhard C Danner, Christian Brandts, Reinhard Büttner, Martin Canis, Kimberly Stegmaier, Hubert Serve, Henning Urlaub, Thomas Oellerich
Published 2018-09-01