The Development of Compartmentation of cAMP Signaling in Cardiomyocytes: The Role of T-Tubules and Caveolae Microdomains

by Navneet K. Bhogal, Alveera Hasan, Julia Gorelik
Published 2018-05-01

Electrophysiological Remodeling: Cardiac T-Tubules and ß-Adrenoceptors

by Peter T. Wright, Julia Gorelik, Sian E. Harding
Published 2021-09-01

Editorial: Cardiomyocyte Microdomains: An Emerging Concept of Local Regulation and Remodeling

by Di Lang, Sarah C. Calaghan, Julia Gorelik, Alexey V. Glukhov
Published 2020-05-01

Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

by Hariharan Subramanian, Alexander Froese, Peter Jönsson, Hannes Schmidt, Julia Gorelik, Viacheslav O. Nikolaev
Published 2018-06-01

Age-Dependent Maturation of iPSC-CMs Leads to the Enhanced Compartmentation of β₂AR-cAMP Signalling

by Alveera Hasan, Neda Mohammadi, Aisha Nawaz, Thusharika Kodagoda, Ivan Diakonov, Sian E. Harding, Julia Gorelik
Published 2020-10-01

Exosomes: From Potential Culprits to New Therapeutic Promise in the Setting of Cardiac Fibrosis

by Roman Tikhomirov, Benedict Reilly-O’ Donnell, Francesco Catapano, Giuseppe Faggian, Julia Gorelik, Fabio Martelli, Costanza Emanueli
Published 2020-03-01

Correction: Shape and Compliance of Endothelial Cells after Shear Stress In Vitro or from Different Aortic Regions: Scanning Ion Conductance Microscopy Study

by Claire M. F. Potter, Sophie Schobesberger, Martina H. Lundberg, Peter D. Weinberg, Jane A. Mitchell, Julia Gorelik
Published 2012-01-01

Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study.

by Claire M F Potter, Sophie Schobesberger, Martina H Lundberg, Peter D Weinberg, Jane A Mitchell, Julia Gorelik
Published 2012-01-01

Correction: Shape and Compliance of Endothelial Cells after Shear Stress In Vitro or from Different Aortic Regions: Scanning Ion Conductance Microscopy Study.

by Claire M. F. Potter, Sophie Schobesberger, Martina H. Lundberg, Peter D. Weinberg, Jane A. Mitchell, Julia Gorelik
Published 2012-01-01

Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis.

by Oladipupo Adeyemi, Anita Alvarez-Laviada, Francisca Schultz, Effendi Ibrahim, Michael Trauner, Catherine Williamson, Alexey V Glukhov, Julia Gorelik
Published 2017-01-01

Bile acids and their respective conjugates elicit different responses in neonatal cardiomyocytes: role of Gi protein, muscarinic receptors and TGR5

by Effendi Ibrahim, Ivan Diakonov, Dulasi Arunthavarajah, Teresa Swift, Mary Goodwin, Saraid McIlvride, Vanya Nikolova, Catherine Williamson, Julia Gorelik
Published 2018-05-01

Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc

by Hua-Qian Yang, Marta Pérez-Hernández, Jose Sanchez-Alonso, Andriy Shevchuk, Julia Gorelik, Eli Rothenberg, Mario Delmar, William A Coetzee
Published 2020-01-01

Junction Mapper is a novel computer vision tool to decipher cell–cell contact phenotypes

by Helena Brezovjakova, Chris Tomlinson, Noor Mohd Naim, Pamela Swiatlowska, Jennifer C Erasmus, Stephan Huveneers, Julia Gorelik, Susann Bruche, Vania MM Braga
Published 2019-12-01

Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies.

by Jose L. Sanchez-Alonso, Alexandra Loucks, Sophie Schobesberger, Ankie M. van Cromvoirt, Claire Poulet, Rasheda A. Chowdhury, Natalia Trayanova, Julia Gorelik
Published 2020-07-01

Prolonged ursodeoxycholic acid administration reduces acute ischaemia-induced arrhythmias in adult rat hearts

by Elisa Ferraro, Lidia Pozhidaeva, David S. Pitcher, Catherine Mansfield, Jia Han Benjamin Koh, Catherine Williamson, Oleg Aslanidi, Julia Gorelik, Fu Siong Ng
Published 2020-09-01

Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes.

by Siti H Sheikh Abdul Kadir, Michele Miragoli, Shadi Abu-Hayyeh, Alexey V Moshkov, Qilian Xie, Verena Keitel, Viacheslav O Nikolaev, Catherine Williamson, Julia Gorelik
Published 2010-03-01

β3-Adrenoceptor redistribution impairs NO/cGMP/PDE2 signalling in failing cardiomyocytes

by Sophie Schobesberger, Peter T Wright, Claire Poulet, Jose L Sanchez Alonso Mardones, Catherine Mansfield, Andreas Friebe, Sian E Harding, Jean-Luc Balligand, Viacheslav O Nikolaev, Julia Gorelik
Published 2020-03-01

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

by Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik
Published 2018-09-01

Local hyperactivation of L-type Ca2+ channels increases spontaneous Ca2+ release activity and cellular hypertrophy in right ventricular myocytes from heart failure rats

by Roman Y. Medvedev, Jose L. Sanchez-Alonso, Catherine A. Mansfield, Aleksandra Judina, Alice J. Francis, Christina Pagiatakis, Natalia Trayanova, Alexey V. Glukhov, Michele Miragoli, Giuseppe Faggian, Julia Gorelik
Published 2021-03-01

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

by Nicoletta C. Surdo, Marco Berrera, Andreas Koschinski, Marcella Brescia, Matias R. Machado, Carolyn Carr, Peter Wright, Julia Gorelik, Stefano Morotti, Eleonora Grandi, Donald M. Bers, Sergio Pantano, Manuela Zaccolo
Published 2017-04-01