QT interval prolongation and with donepezil, rivastigmine and galantamine

by Katie Malone, Jules C. Hancox
Published 2020-08-01

Electrophysiological characterization of the modified hERGT potassium channel used to obtain the first cryo‐EM hERG structure

by Yihong Zhang, Christopher E. Dempsey, Jules C. Hancox
Published 2020-10-01

Synthetic cannabinoids and potential cardiac arrhythmia risk: an important message for drug users

by Jules C. Hancox, Nicola J. Kalk, Graeme Henderson
Published 2020-03-01

In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel—A Drug Antitarget

by Ehab Al-Moubarak, Mohsen Sharifi, Jules C. Hancox
Published 2021-05-01

In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome

by Dominic G. Whittaker, Dominic G. Whittaker, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2019-01-01

Functional evaluation of gene mutations in Long QT Syndrome: strength of evidence from in vitro assays for deciphering variants of uncertain significance

by Jules C. Hancox, Alan G. Stuart, Stephen C. Harmer
Published 2020-11-01

In silico investigation of pro-arrhythmic effects of azithromycin on the human ventricle

by Yizhou Liu, Rai Zhang, Jules C. Hancox, Henggui Zhang
Published 2021-09-01

Cardiac Pacemaker Dysfunction Arising From Different Studies of Ion Channel Remodeling in the Aging Rat Heart

by Aaazh M. Alghamdi, Aaazh M. Alghamdi, Mark R. Boyett, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2020-12-01

The Functional Role of Hyperpolarization Activated Current (If) on Cardiac Pacemaking in Human vs. in the Rabbit Sinoatrial Node: A Simulation and Theoretical Study

by Xiangyun Bai, Xiangyun Bai, Xiangyun Bai, Kuanquan Wang, Mark R. Boyett, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2021-08-01

Computational Analysis of the Mode of Action of Disopyramide and Quinidine on hERG-Linked Short QT Syndrome in Human Ventricles

by Dominic G. Whittaker, Haibo Ni, Alan P. Benson, Alan P. Benson, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2017-10-01

Reciprocal interaction between IK1 and If in biological pacemakers: A simulation study.

by Yacong Li, Kuanquan Wang, Qince Li, Jules C Hancox, Henggui Zhang
Published 2021-03-01

Learning from studying very rare cardiac conditions: the example of short QT syndrome

by Jules C. Hancox, Dominic G. Whittaker, Henggui Zhang, Alan G. Stuart
Published 2019-04-01

Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models.

by Marta Varela, Michael A Colman, Jules C Hancox, Oleg V Aslanidi
Published 2016-12-01

Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy

by Michael Gysel, Alexander Crystal, Jules C. Hancox, Michelle Methot, Adrian Baranchuk
Published 2014-01-01

Triadin mutations - a cause of ventricular arrhythmias in children and young adults

by Jules C. Hancox, Andrew F. James, Mark A. Walsh, Alan G. Stuart
Published 2017-10-01

Mechanistic Insights Into the Reduced Pacemaking Rate of the Rabbit Sinoatrial Node During Postnatal Development: A Simulation Study

by Azzah M. Alghamdi, Azzah M. Alghamdi, Craig P. Testrow, Dominic G. Whittaker, Mark R. Boyett, Jules. C. Hancox, Jules. C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2020-11-01

Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling

by Dominic G. Whittaker, Dominic G. Whittaker, Michael A. Colman, Haibo Ni, Haibo Ni, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang, Henggui Zhang
Published 2018-10-01

Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria.

by Dominic G Whittaker, Haibo Ni, Aziza El Harchi, Jules C Hancox, Henggui Zhang
Published 2017-06-01

In silico investigation of a KCNQ1 mutation associated with short QT syndrome

by Ismail Adeniran, Dominic G. Whittaker, Aziza El Harchi, Jules C. Hancox, Henggui Zhang
Published 2017-08-01

Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome

by Andrew Butler, Yihong Zhang, A. Graham Stuart, Christopher E. Dempsey, Jules C. Hancox
Published 2019-04-01