Mutations primarily alter the inclusion of alternatively spliced exons

by Pablo Baeza-Centurion, Belén Miñana, Juan Valcárcel, Ben Lehner
Published 2020-10-01

Alternative Splicing and Cancer

by Didier Auboeuf, Maria Carmo-Fonseca, Juan Valcarcel, Giuseppe Biamonti
Published 2012-01-01

Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP

by Luisa Vigevani, André Gohr, Thomas Webb, Manuel Irimia, Juan Valcárcel
Published 2017-12-01

The complete local genotype–phenotype landscape for the alternative splicing of a human exon

by Philippe Julien, Belén Miñana, Pablo Baeza-Centurion, Juan Valcárcel, Ben Lehner
Published 2016-05-01

Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns

by Sandra Keiper, Panagiotis Papasaikas, Cindy L. Will, Juan Valcárcel, Cyrille Girard, Reinhard Lührmann
Published 2019-08-01

Structural basis for the recognition of spliceosomal SmN/B/B’ proteins by the RBM5 OCRE domain in splicing regulation

by André Mourão, Sophie Bonnal, Komal Soni, Lisa Warner, Rémy Bordonné, Juan Valcárcel, Michael Sattler
Published 2016-11-01

Regulation of FAS Exon Definition and Apoptosis by the Ewing Sarcoma Protein

by Maria Paola Paronetto, Isabella Bernardis, Elisabetta Volpe, Elias Bechara, Endre Sebestyén, Eduardo Eyras, Juan Valcárcel
Published 2014-05-01

Co-option of the piRNA Pathway for Germline-Specific Alternative Splicing of C. elegans TOR

by Sergio Barberán-Soler, Laura Fontrodona, Anna Ribó, Ayelet T. Lamm, Camilla Iannone, Julián Cerón, Ben Lehner, Juan Valcárcel
Published 2014-09-01

Functional Network Analysis Reveals the Relevance of SKIIP in the Regulation of Alternative Splicing by p38 SAPK

by Caterina Carbonell, Arnau Ulsamer, Claudia Vivori, Panagiotis Papasaikas, René Böttcher, Manel Joaquin, Belén Miñana, Juan Ramón Tejedor, Eulàlia de Nadal, Juan Valcárcel, Francesc Posas
Published 2019-04-01

Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1

by Claudia Vivori, Panagiotis Papasaikas, Ralph Stadhouders, Bruno Di Stefano, Anna Ribó Rubio, Clara Berenguer Balaguer, Serena Generoso, Anna Mallol, José Luis Sardina, Bernhard Payer, Thomas Graf, Juan Valcárcel
Published 2021-06-01

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

by Metehan Cifdaloz, Lisa Osterloh, Osvaldo Graña, Erica Riveiro-Falkenbach, Pilar Ximénez-Embún, Javier Muñoz, Cristina Tejedo, Tonantzin G. Calvo, Panagiotis Karras, David Olmeda, Belén Miñana, Gonzalo Gómez-López, Estela Cañon, Eduardo Eyras, Haihong Guo, Ferdinand Kappes, Pablo L. Ortiz-Romero, Jose L. Rodríguez-Peralto, Diego Megías, Juan Valcárcel, María S. Soengas
Published 2017-12-01

Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice

by Keiko Horiuchi, Serafín Perez-Cerezales, Panagiotis Papasaikas, Priscila Ramos-Ibeas, Angela Patricia López-Cardona, Ricardo Laguna-Barraza, Noelia Fonseca Balvís, Eva Pericuesta, Raul Fernández-González, Benjamín Planells, Alberto Viera, Jose Angel Suja, Pablo Juan Ross, Francisco Alén, Laura Orio, Fernando Rodriguez de Fonseca, Belén Pintado, Juan Valcárcel, Alfonso Gutiérrez-Adán
Published 2018-04-01