Anti-apoptotic and Matrix Remodeling Actions of a Small Molecule Agonist of the Human Relaxin Receptor, ML290 in Mice With Unilateral Ureteral Obstruction

by Hooi Hooi Ng, Mariluz Soula, Bryan Rivas, Kenneth J. Wilson, Juan J. Marugan, Alexander I. Agoulnik
Published 2021-07-01

Plasma and Tissue Concentrations of α-Tocopherol and δ-Tocopherol Following High Dose Dietary Supplementation in Mice

by William J. Pavan, Wei Zheng, John C. McKew, Art Incao, Juan J. Marugan, Jingbo Xiao, Laura L. Baxter
Published 2012-06-01

Novel patient cell-based HTS assay for identification of small molecules for a lysosomal storage disease.

by Haifeng Geng, Grace Whiteley, Jameson Ribbens, Wei Zheng, Noel Southall, Xin Hu, Juan J Marugan, Marc Ferrer, Gustavo H B Maegawa
Published 2011-01-01

Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses

by Ni Sima, Rong Li, Wei Huang, Miao Xu, Jeanette Beers, Jizhong Zou, Steven Titus, Elizabeth A. Ottinger, Juan J. Marugan, Xing Xie, Wei Zheng
Published 2018-04-01

Identification of a G-Protein-Independent Activator of GIRK Channels

by Yulin Zhao, Peter Man-Un Ung, Gergely Zahoránszky-Kőhalmi, Alexey V. Zakharov, Natalia J. Martinez, Anton Simeonov, Ian W. Glaaser, Ganesha Rai, Avner Schlessinger, Juan J. Marugan, Paul A. Slesinger
Published 2020-06-01

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1

by Martina Kocan, Mohsin Sarwar, Sheng Y. Ang, Jingbo Xiao, Juan J. Marugan, Mohammed A. Hossain, Chao Wang, Dana S. Hutchinson, Chrishan S. Samuel, Alexander I. Agoulnik, Ross A. D. Bathgate, Roger J. Summers
Published 2017-06-01

A high throughput screening assay system for the identification of small molecule inhibitors of gsp.

by Nisan Bhattacharyya, Xin Hu, Catherine Z Chen, Lesley A Mathews Griner, Wei Zheng, James Inglese, Christopher P Austin, Juan J Marugan, Noel Southall, Susanne Neumann, John K Northup, Marc Ferrer, Michael T Collins
Published 2014-01-01

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.

by Rupkatha Mukhopadhyay, Sujayita Roy, Rajkumar Venkatadri, Yu-Pin Su, Wenjuan Ye, Elena Barnaeva, Lesley Mathews Griner, Noel Southall, Xin Hu, Amy Q Wang, Xin Xu, Andrés E Dulcey, Juan J Marugan, Marc Ferrer, Ravit Arav-Boger
Published 2016-06-01

Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease

by Mylinh Vu, Rong Li, Amanda Baskfield, Billy Lu, Atena Farkhondeh, Kirill Gorshkov, Omid Motabar, Jeanette Beers, Guokai Chen, Jizhong Zou, Angela J. Espejo-Mojica, Alexander Rodríguez-López, Carlos J. Alméciga-Díaz, Luis A. Barrera, Xuntian Jiang, Daniel S. Ory, Juan J. Marugan, Wei Zheng
Published 2018-09-01