Potential Treatment of Retinal Diseases with Iron Chelators

by Wanting Shu, Joshua L. Dunaief
Published 2018-10-01

Retinal iron homeostasis in health and disease

by Delu eSong, Joshua L. Dunaief
Published 2013-06-01

Ferrous but not ferric iron sulfate kills photoreceptors and induces photoreceptor-dependent RPE autofluorescence

by Wanting Shu, Bailey H. Baumann, Ying Song, Yingrui Liu, Xingwei Wu, Joshua L. Dunaief
Published 2020-07-01

Dexras1 Deletion and Iron Chelation Promote Neuroprotection in Experimental Optic Neuritis

by Reas S. Khan, Bailey Baumann, Kimberly Dine, Ying Song, Joshua L. Dunaief, Sangwon F. Kim, Kenneth S. Shindler
Published 2019-08-01

Bull's eye maculopathy associated with hereditary hemochromatosis

by Kellyn N. Bellsmith, Joshua L. Dunaief, Paul Yang, Mark E. Pennesi, Ellen Davis, Holly Hofkamp, Brandon J. Lujan
Published 2020-06-01

Mechanisms that minimize retinal impact of apolipoprotein E absence[S]

by Aicha Saadane, Alexey Petrov, Natalia Mast, Nicole El-Darzi, Tung Dao, Ahab Alnemri, Ying Song, Joshua L. Dunaief, Irina A. Pikuleva
Published 2018-12-01

GLP-1 Receptor Agonist NLY01 Reduces Retinal Inflammation and Neuron Death Secondary to Ocular Hypertension

by Jacob K. Sterling, Modupe O. Adetunji, Samyuktha Guttha, Albert R. Bargoud, Katherine E. Uyhazi, Ahmara G. Ross, Joshua L. Dunaief, Qi N. Cui
Published 2020-11-01

Persistent and Progressive Outer Retina Thinning in Frontotemporal Degeneration

by Benjamin J. Kim, Murray Grossman, Delu Song, Samantha Saludades, Wei Pan, Sophia Dominguez-Perez, Joshua L. Dunaief, Tomas S. Aleman, Gui-Shuang Ying, David J. Irwin
Published 2019-04-01

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.

by Delu Song, Brooks Wilson, Liangliang Zhao, Rupak Bhuyan, Mausumi Bandyopadhyay, Arkady Lyubarsky, Chen Yu, Yafeng Li, Levi Kanu, Takashi Miwa, Wen-Chao Song, Silvia C Finnemann, Bärbel Rohrer, Joshua L Dunaief
Published 2016-01-01

Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and CeruloplasminSummary

by Brie K. Fuqua, Yan Lu, David M. Frazer, Deepak Darshan, Sarah J. Wilkins, Linda Dunn, Alex V. Loguinov, Scott C. Kogan, Pavle Matak, Huijun Chen, Joshua L. Dunaief, Chris D. Vulpe, Gregory J. Anderson
Published 2018-01-01

The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice.

by Brie K Fuqua, Yan Lu, Deepak Darshan, David M Frazer, Sarah J Wilkins, Natalie Wolkow, Austin G Bell, JoAnn Hsu, Catherine C Yu, Huijun Chen, Joshua L Dunaief, Gregory J Anderson, Chris D Vulpe
Published 2014-01-01

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome

by Bradley D. Gelfand, Charles B. Wright, Younghee Kim, Tetsuhiro Yasuma, Reo Yasuma, Shengjian Li, Benjamin J. Fowler, Ana Bastos-Carvalho, Nagaraj Kerur, Annette Uittenbogaard, Youn Seon Han, Dingyuan Lou, Mark E. Kleinman, W. Hayes McDonald, Gabriel Núñez, Philippe Georgel, Joshua L. Dunaief, Jayakrishna Ambati
Published 2015-06-01

Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration

by Federica Storti, Katrin Klee, Vyara Todorova, Regula Steiner, Alaa Othman, Saskia van der Velde-Visser, Marijana Samardzija, Isabelle Meneau, Maya Barben, Duygu Karademir, Valda Pauzuolyte, Sanford L Boye, Frank Blaser, Christoph Ullmer, Joshua L Dunaief, Thorsten Hornemann, Lucia Rohrer, Anneke den Hollander, Arnold von Eckardstein, Jürgen Fingerle, Cyrille Maugeais, Christian Grimm
Published 2019-03-01