Acute Genetic Ablation of Cardiac Sodium/Calcium Exchange in Adult Mice: Implications for Cardiomyocyte Calcium Regulation, Cardioprotection, and Arrhythmia

by Sabine Lotteau, Rui Zhang, Adina Hazan, Christina Grabar, Devina Gonzalez, Stephan Aynaszyan, Kenneth D. Philipson, Michela Ottolia, Joshua I. Goldhaber
Published 2021-09-01

Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia

by Nils Bögeholz, Paul Pauls, Paul Pauls, Dirk G. Dechering, Gerrit Frommeyer, Joshua I. Goldhaber, Christian Pott, Lars Eckardt, Frank U. Müller, Jan S. Schulte
Published 2018-08-01

Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity.

by Sabine Groenke, Eric D Larson, Sarah Alber, Rui Zhang, Scott T Lamp, Xiaoyan Ren, Haruko Nakano, Maria C Jordan, Hrayr S Karagueuzian, Kenneth P Roos, Atsushi Nakano, Catherine Proenza, Kenneth D Philipson, Joshua I Goldhaber
Published 2013-01-01

The Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models

by Nils Bögeholz, Jan S. Schulte, Sven Kaese, B. Klemens Bauer, B. Klemens Bauer, Paul Pauls, Paul Pauls, Dirk G. Dechering, Gerrit Frommeyer, Joshua I. Goldhaber, Uwe Kirchhefer, Lars Eckardt, Christian Pott, Frank U. Müller
Published 2017-09-01

Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity

by Hirohito Shimizu, Johann Schredelseker, Jie Huang, Kui Lu, Shamim Naghdi, Fei Lu, Sarah Franklin, Hannah DG Fiji, Kevin Wang, Huanqi Zhu, Cheng Tian, Billy Lin, Haruko Nakano, Amy Ehrlich, Junichi Nakai, Adam Z Stieg, James K Gimzewski, Atsushi Nakano, Joshua I Goldhaber, Thomas M Vondriska, György Hajnóczky, Ohyun Kwon, Jau-Nian Chen
Published 2015-01-01