Mining methylation for early detection of common cancers.

by Romulo M Brena, Christoph Plass, Joseph F Costello
Published 2006-12-01

Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution

by Martin Kircher, Chenling Xiong, Beth Martin, Max Schubach, Fumitaka Inoue, Robert J. A. Bell, Joseph F. Costello, Jay Shendure, Nadav Ahituv
Published 2019-08-01

Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma

by Marina Radoul, Donghyun Hong, Anne Marie Gillespie, Chloé Najac, Pavithra Viswanath, Russell O. Pieper, Joseph F. Costello, Hema Artee Luchman, Sabrina M. Ronen
Published 2021-02-01

Non-invasive assessment of telomere maintenance mechanisms in brain tumors

by Pavithra Viswanath, Georgios Batsios, Joydeep Mukherjee, Anne Marie Gillespie, Peder E. Z. Larson, H. Artee Luchman, Joanna J. Phillips, Joseph F. Costello, Russell O. Pieper, Sabrina M. Ronen
Published 2021-01-01

Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome

by Junchen Gu, Michael Stevens, Xiaoyun Xing, Daofeng Li, Bo Zhang, Jacqueline E. Payton, Eugene M. Oltz, James N. Jarvis, Kaiyu Jiang, Theodore Cicero, Joseph F. Costello, Ting Wang
Published 2016-04-01

Characterization of the contradictory chromatin signatures at the 3' exons of zinc finger genes.

by Kimberly R Blahnik, Lei Dou, Lorigail Echipare, Sushma Iyengar, Henriette O'Geen, Erica Sanchez, Yongjun Zhao, Marco A Marra, Martin Hirst, Joseph F Costello, Ian Korf, Peggy J Farnham
Published 2011-02-01

To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes

by Amelia D. Wallace, George A. Wendt, Lisa F. Barcellos, Adam J. de Smith, Kyle M. Walsh, Catherine Metayer, Joseph F. Costello, Joseph L. Wiemels, Joseph L. Wiemels, Stephen S. Francis, Stephen S. Francis
Published 2018-08-01

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

by Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh
Published 2017-12-01

HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth

by Kurosh Ameri, Arman Jahangiri, Anthony M. Rajah, Kathryn V. Tormos, Ravi Nagarajan, Melike Pekmezci, Vien Nguyen, Matthew L. Wheeler, Michael P. Murphy, Timothy A. Sanders, Stefanie S. Jeffrey, Yerem Yeghiazarians, Paolo F. Rinaudo, Joseph F. Costello, Manish K. Aghi, Emin Maltepe
Published 2015-02-01

Multiplatform Molecular Profiling Reveals Epigenomic Intratumor Heterogeneity in Ependymoma

by S. John Liu, Stephen T. Magill, Harish N. Vasudevan, Stephanie Hilz, Javier E. Villanueva-Meyer, Sydney Lastella, Vikas Daggubati, Jordan Spatz, Abrar Choudhury, Brent A. Orr, Benjamin Demaree, Kyounghee Seo, Sean P. Ferris, Adam R. Abate, Nancy Ann Oberheim Bush, Andrew W. Bollen, Michael W. McDermott, Joseph F. Costello, David R. Raleigh
Published 2020-02-01

Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma

by Stephen T. Magill, Harish N. Vasudevan, Kyounghee Seo, Javier E. Villanueva-Meyer, Abrar Choudhury, S. John Liu, Melike Pekmezci, Sarah Findakly, Stephanie Hilz, Sydney Lastella, Benjamin Demaree, Steve E. Braunstein, Nancy Ann Oberheim Bush, Manish K. Aghi, Philip V. Theodosopoulos, Penny K. Sneed, Adam R. Abate, Mitchel S. Berger, Michael W. McDermott, Daniel A. Lim, Erik M. Ullian, Joseph F. Costello, David R. Raleigh
Published 2020-09-01

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

by Christina L. Zheng, Nicholas J. Wang, Jongsuk Chung, Homayoun Moslehi, J. Zachary Sanborn, Joseph S. Hur, Eric A. Collisson, Swapna S. Vemula, Agne Naujokas, Kami E. Chiotti, Jeffrey B. Cheng, Hiva Fassihi, Andrew J. Blumberg, Celeste V. Bailey, Gary M. Fudem, Frederick G. Mihm, Bari B. Cunningham, Isaac M. Neuhaus, Wilson Liao, Dennis H. Oh, James E. Cleaver, Philip E. LeBoit, Joseph F. Costello, Alan R. Lehmann, Joe W. Gray, Paul T. Spellman, Sarah T. Arron, Nam Huh, Elizabeth Purdom, Raymond J. Cho
Published 2014-11-01