Neural Differentiation Is Inhibited through HIF1α/β-Catenin Signaling in Embryoid Bodies

by Josef Večeřa, Jana Kudová, Jan Kučera, Lukáš Kubala, Jiří Pacherník
Published 2017-01-01

Apocynin and Diphenyleneiodonium Induce Oxidative Stress and Modulate PI3K/Akt and MAPK/Erk Activity in Mouse Embryonic Stem Cells

by Jan Kučera, Lucia Binó, Kateřina Štefková, Josef Jaroš, Ondřej Vašíček, Josef Večeřa, Lukáš Kubala, Jiří Pacherník
Published 2016-01-01

Hypoxia/Hif1α prevents premature neuronal differentiation of neural stem cells through the activation of Hes1

by Josef Večeřa, Jiřina Procházková, Veronika Šumberová, Veronika Pánská, Hana Paculová, Martina Kohutková Lánová, Jan Mašek, Dáša Bohačiaková, Emma Rachel Andersson, Jiří Pacherník
Published 2020-05-01

Differentiation of neural rosettes from human pluripotent stem cells in vitro is sequentially regulated on a molecular level and accomplished by the mechanism reminiscent of second...

by Veronika Fedorova, Tereza Vanova, Lina Elrefae, Jakub Pospisil, Martina Petrasova, Veronika Kolajova, Zuzana Hudacova, Jana Baniariova, Martin Barak, Lucie Peskova, Tomas Barta, Marketa Kaucka, Michael Killinger, Josef Vecera, Ondrej Bernatik, Lukas Cajanek, Hana Hribkova, Dasa Bohaciakova
Published 2019-10-01