Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA

by José Antonio Encinar, Javier A. Menendez
Published 2020-05-01

Silibinin and SARS-CoV-2: Dual Targeting of Host Cytokine Storm and Virus Replication Machinery for Clinical Management of COVID-19 Patients

by Joaquim Bosch-Barrera, Begoña Martin-Castillo, Maria Buxó, Joan Brunet, José Antonio Encinar, Javier A. Menendez
Published 2020-06-01

Antiviral Activity of a Turbot (<i>Scophthalmus maximus</i>) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion

by Alberto Falco, Regla María Medina-Gali, José Antonio Poveda, Melissa Bello-Perez, Beatriz Novoa, José Antonio Encinar
Published 2019-02-01

Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity

by María Herranz-López, Mariló Olivares-Vicente, José Antonio Encinar, Enrique Barrajón-Catalán, Antonio Segura-Carretero, Jorge Joven, Vicente Micol
Published 2017-08-01

New Mammalian Target of Rapamycin (mTOR) Modulators Derived from Natural Product Databases and Marine Extracts by Using Molecular Docking Techniques

by Verónica Ruiz-Torres, Maria Losada-Echeberría, Maria Herranz-López, Enrique Barrajón-Catalán, Vicente Galiano, Vicente Micol, José Antonio Encinar
Published 2018-10-01

De novo polymerase activity and oligomerization of hepatitis C virus RNA-dependent RNA-polymerases from genotypes 1 to 5.

by Pilar Clemente-Casares, Alberto J López-Jiménez, Itxaso Bellón-Echeverría, José Antonio Encinar, Elisa Martínez-Alfaro, Ricardo Pérez-Flores, Antonio Mas
Published 2011-04-01

pH-Dependent Solution Structure and Activity of a Reduced Form of the Host-Defense Peptide Myticin C (Myt C) from the Mussel Mytilus galloprovincialis

by Amparo Estepa, Antonio Figueras, Beatriz Novoa, Pablo Garcia-Valtanen, Pablo Balseiro, Jose Antonio Encinar, Regla Maria Medina-Gali, Alicia Martinez-Lopez
Published 2013-07-01

IFIT5 Participates in the Antiviral Mechanisms of Rainbow Trout Red Blood Cells

by Veronica Chico, Veronica Chico, Maria Elizabhet Salvador-Mira, Maria Elizabhet Salvador-Mira, Ivan Nombela, Ivan Nombela, Sara Puente-Marin, Sara Puente-Marin, Sergio Ciordia, María Carmen Mena, Luis Perez, Luis Perez, Julio Coll, Fanny Guzman, Jose Antonio Encinar, Jose Antonio Encinar, Luis Mercado, Maria del Mar Ortega-Villaizan, Maria del Mar Ortega-Villaizan
Published 2019-04-01

AMPK modulatory activity of olive-tree leaves phenolic compounds: Bioassay-guided isolation on adipocyte model and in silico approach.

by Cecilia Jiménez-Sánchez, Mariló Olivares-Vicente, Celia Rodríguez-Pérez, María Herranz-López, Jesús Lozano-Sánchez, Antonio Segura-Carretero, Alberto Fernández-Gutiérrez, José Antonio Encinar, Vicente Micol
Published 2017-01-01

Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2

by Angela Tramonti, Elisabet Cuyàs, José Antonio Encinar, Matthias Pietzke, Alessio Paone, Sara Verdura, Aina Arbusà, Begoña Martin-Castillo, Giorgio Giardina, Jorge Joven, Alexei Vazquez, Roberto Contestabile, Francesca Cutruzzolà, Javier A. Menendez
Published 2021-08-01

Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A

by Elisabet Cuyàs, Juan Gumuzio, Jesús Lozano-Sánchez, David Carreras, Sara Verdura, Laura Llorach-Parés, Melchor Sanchez-Martinez, Elisabet Selga, Guillermo J. Pérez, Fabiana S. Scornik, Ramon Brugada, Joaquim Bosch-Barrera, Antonio Segura-Carretero, Ángel G. Martin, José Antonio Encinar, Javier A. Menendez
Published 2019-07-01