pH Sensing and Regulation in Cancer

by Mehdi eDamaghi, Jonathan W. Wojtkowiak, Robert J. Gillies
Published 2013-12-01

MR Imaging Biomarkers to Monitor Early Response to Hypoxia-Activated Prodrug TH-302 in Pancreatic Cancer Xenografts.

by Xiaomeng Zhang, Jonathan W Wojtkowiak, Gary V Martinez, Heather H Cornnell, Charles P Hart, Amanda F Baker, Robert Gillies
Published 2016-01-01

Mechanisms of buffer therapy resistance

by Kate M. Bailey, Jonathan W. Wojtkowiak, Heather H. Cornnell, Maria C. Ribeiro, Yoganand Balagurunathan, Arig Ibrahim Hashim, Robert J. Gillies
Published 2014-04-01

Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer.

by Kate M Bailey, Heather H Cornnell, Arig Ibrahim-Hashim, Jonathan W Wojtkowiak, Charles P Hart, Xiaomeng Zhang, Rafael Leos, Gary V Martinez, Amanda F Baker, Robert J Gillies
Published 2014-01-01

Acid-Mediated Tumor Proteolysis: Contribution of Cysteine Cathepsins

by Jennifer M Rothberg, Kate M Bailey, Jonathan W Wojtkowiak, Yael Ben-Nun, Matthew Bogyo, Ekkehard Weber, Kamiar Moin, Galia Blum, Raymond R Mattingly, Robert J Gillies, Bonnie F Sloane
Published 2013-10-01

Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.

by Yoichi Takakusagi, Shingo Matsumoto, Keita Saito, Masayuki Matsuo, Shun Kishimoto, Jonathan W Wojtkowiak, William DeGraff, Aparna H Kesarwala, Rajani Choudhuri, Nallathamby Devasahayam, Sankaran Subramanian, Jeeva P Munasinghe, Robert J Gillies, James B Mitchell, Charles P Hart, Murali C Krishna
Published 2014-01-01