Jonathan Stamler
Jonathan Solomon Stamler (born June 23, 1959) is an English-born American physician and scientist. He is known for his discovery of
protein S-nitrosylation, the addition of a
nitric oxide (NO) group to
cysteine residues in proteins, as a ubiquitous cellular signal to regulate
enzymatic activity and other key protein functions in bacteria, plants and animals, and particularly in transporting NO on cysteines in
hemoglobin as the third gas in the
respiratory cycle.
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