Cell Receptor and Cofactor Interactions of the Contact Activation System and Factor XI

by Monika Pathak, Bubacarr Gibril Kaira, Alexandre Slater, Jonas Emsley
Published 2018-03-01

Crystal structure and substrate-induced activation of ADAMTS13

by Anastasis Petri, Hyo Jung Kim, Yaoxian Xu, Rens de Groot, Chan Li, Aline Vandenbulcke, Karen Vanhoorelbeke, Jonas Emsley, James T. B. Crawley
Published 2019-08-01

Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR).

by Aravindan Ilangovan, Matthew Fletcher, Giordano Rampioni, Christian Pustelny, Kendra Rumbaugh, Stephan Heeb, Miguel Cámara, Alex Truman, Siri Ram Chhabra, Jonas Emsley, Paul Williams
Published 2013-01-01

Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module

by Nicholas A. Arce, Wenpeng Cao, Alexander K. Brown, Emily R. Legan, Moriah S. Wilson, Emma-Ruoqi Xu, Michael C. Berndt, Jonas Emsley, X. Frank Zhang, Renhao Li
Published 2021-04-01

Factor XII in PMM2-CDG patients: role of N-glycosylation in the secretion and function of the first element of the contact pathway

by Raquel López-Gálvez, María Eugenia de la Morena-Barrio, Alberto López-Lera, Monika Pathak, Antonia Miñano, Mercedes Serrano, Delphine Borgel, Vanessa Roldán, Vicente Vicente, Jonas Emsley, Javier Corral
Published 2020-10-01

Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

by Fadi Soukarieh, Fadi Soukarieh, Ruiling Liu, Manuel Romero, Manuel Romero, Shaun N. Roberston, Shaun N. Roberston, William Richardson, Simone Lucanto, Simone Lucanto, Eduard Vico Oton, Naim Ruhul Qudus, Alaa Mashabi, Scott Grossman, Sadiqur Ali, Tomás Sou, Tomás Sou, Irena Kukavica-Ibrulj, Roger C. Levesque, Christel A. S. Bergström, Christel A. S. Bergström, Nigel Halliday, Shailesh N. Mistry, Jonas Emsley, Jonas Emsley, Stephan Heeb, Paul Williams, Paul Williams, Miguel Cámara, Miguel Cámara, Michael J. Stocks, Michael J. Stocks
Published 2020-05-01

The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant

by Fernando Corvillo, Fernando Corvillo, María Eugenia de la Morena-Barrio, María Eugenia de la Morena-Barrio, Carmen Marcos-Bravo, Margarita López-Trascasa, Margarita López-Trascasa, Vicente Vicente, Vicente Vicente, Jonas Emsley, Teresa Caballero, Teresa Caballero, Teresa Caballero, Javier Corral, Javier Corral, Alberto López-Lera, Alberto López-Lera
Published 2020-09-01