Using incomplete trios to boost confidence in family based association studies

by Varsha eDhankani, David L Gibbs, Theo eKnijnenburg, Roger eKramer, Joseph eVockley, Joseph eVockley, John eNiederhuber, John eNiederhuber, Ilya eShmulevich, Brady eBernard
Published 2016-03-01

Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants

by Megan S. Kane, Callie J. Diamonstein, Natalie Hauser, John F. Deeken, John E. Niederhuber, Thierry Vilboux
Published 2019-03-01

Collection of non-meconium stool on fecal occult blood cards is an effective method for fecal microbiota studies in infants

by Wendy S.W. Wong, Nicole Clemency, Elisabeth Klein, Marina Provenzano, Ramaswamy Iyer, John E. Niederhuber, Suchitra K. Hourigan
Published 2017-09-01

CloudForest: A Scalable and Efficient Random Forest Implementation for Biological Data.

by Ryan Bressler, Richard B Kreisberg, Brady Bernard, John E Niederhuber, Joseph G Vockley, Ilya Shmulevich, Theo A Knijnenburg
Published 2015-01-01

Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

by Dale L Bodian, Justine N McCutcheon, Prachi Kothiyal, Kathi C Huddleston, Ramaswamy K Iyer, Joseph G Vockley, John E Niederhuber
Published 2014-01-01

Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer.

by Christina H Stuelten, Johanna I Busch, Binwu Tang, Kathleen C Flanders, Akira Oshima, Emily Sutton, Tatiana S Karpova, Anita B Roberts, Lalage M Wakefield, John E Niederhuber
Published 2010-01-01

SDF-1α mediates wound-promoted tumor growth in a syngeneic orthotopic mouse model of breast cancer.

by Christina H Stuelten, Frances N Cervoni-Curet, Johanna I Busch, Emily Sutton, Joshua D Webster, Sandra L Kavalukas, Lalage M Wakefield, Adrian Barbul, John E Niederhuber
Published 2013-01-01

A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept.

by Susan D Mertins, Dominic A Scudiero, Melinda G Hollingshead, Raymond D Divelbiss, Michael C Alley, Anne Monks, David G Covell, Karen M Hite, David S Salomon, John E Niederhuber
Published 2013-01-01

Studying the urine microbiome in superficial bladder cancer: samples obtained by midstream voiding versus cystoscopy

by Suchitra K. Hourigan, Wei Zhu, Wendy S.W.Wong, Nicole C. Clemency, Marina Provenzano, Thierry Vilboux, John E. Niederhuber, John Deeken, Simon Chung, Kim McDaniel-Wiley, Donald Trump
Published 2020-01-01

New observations on maternal age effect on germline de novo mutations

by Wendy S. W. Wong, Benjamin D. Solomon, Dale L. Bodian, Prachi Kothiyal, Greg Eley, Kathi C. Huddleston, Robin Baker, Dzung C. Thach, Ramaswamy K. Iyer, Joseph G. Vockley, John E. Niederhuber
Published 2016-01-01

Prenatal and Peripartum Exposure to Antibiotics and Cesarean Section Delivery Are Associated with Differences in Diversity and Composition of the Infant Meconium Microbiome

by Wendy S.W. Wong, Priya Sabu, Varsha Deopujari, Shira Levy, Ankit A. Shah, Nicole Clemency, Marina Provenzano, Reem Saadoon, Akhil Munagala, Robin Baker, Rajiv Baveja, Noel T. Mueller, Maria Gloria Dominguez-Bello, Kathi Huddleston, John E. Niederhuber, Suchitra K. Hourigan
Published 2020-01-01

Comparison of Infant Gut and Skin Microbiota, Resistome and Virulome Between Neonatal Intensive Care Unit (NICU) Environments

by Suchitra K. Hourigan, Suchitra K. Hourigan, Suchitra K. Hourigan, Poorani Subramanian, Nur A. Hasan, Allison Ta, Elisabeth Klein, Nassim Chettout, Kathi Huddleston, Varsha Deopujari, Shira Levy, Rajiv Baveja, Nicole C. Clemency, Robin L. Baker, John E. Niederhuber, Rita R. Colwell
Published 2018-06-01

Identification of copy number variants in whole-genome data using Reference Coverage Profiles

by Gustavo eGlusman, Alissa eSeverson, Varsha eDhankani, Max eRobinson, Terry eFarrah, Denise E. Mauldin, Anna B. Stittrich, Seth A. Ament, Jared C. Roach, Mary E. Brunkow, Dale L. Bodian, Joseph G. Vockley, Ilya eShmulevich, John E. Niederhuber, Leroy eHood
Published 2015-02-01