How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH

by Shen-Han Lee, John R. Griffiths
Published 2020-06-01

HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells

by Shen-Han Lee, Monika Golinska, John R. Griffiths
Published 2021-09-01

Exploration of human brain tumour metabolism using pairwise metabolite-metabolite correlation analysis (MMCA) of HR-MAS 1H NMR spectra.

by Basetti Madhu, Alexandra Jauhiainen, Sean McGuire, John R Griffiths
Published 2017-01-01

Response of Hepatoma 9618a and Normal Liver to Host Carbogen and Carbon Monoxide Breathing

by Simon P. Robinson, Loreta M. Rodrigues, John R. Griffiths, Marion Stubbs
Published 1999-12-01

The Response of RIF-1 Fibrosarcomas to the Vascular-Disrupting Agent ZD6126 Assessed by In Vivo and Ex Vivo1H Magnetic Resonance Spectroscopy

by Basetti Madhu, John C. Waterton, John R. Griffiths, Anderson J. Ryan, Simon P. Robinson
Published 2006-07-01

Absolute Quantification of Endogenous Ras Isoform Abundance.

by Craig J Mageean, John R Griffiths, Duncan L Smith, Michael J Clague, Ian A Prior
Published 2015-01-01

Enhanced Uptake of Ifosfamide into GH3 Prolactinomas with Hypercapnic Hyperoxic Gases Monitored In Vivo by 31P MRS

by Loreta M. Rodrigues, Simon P. Robinson, Paul M.J. McSheehy, Marion Stubbs, John R. Griffiths
Published 2002-01-01

Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis

by Tetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, Harvey T. McMahon, David M. Glover
Published 2013-01-01

Overexpression of Dimethylarginine Dimethylaminohydrolase Enhances Tumor Hypoxia: An Insight into the Relationship of Hypoxia and Angiogenesis In Vivo

by Vassiliki Kostourou, Helen Troy, Joanne F. Murray, Elizabeth R. Cullis, Guy St. J. Whitley, John R. Griffiths, Simon P. Robinson
Published 2004-07-01

Rat Tumor Response to the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid as Measured by Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Plasma 5-Hydroxyindole...

by Lesley D. McPhail, Dominick J.O. McIntyre, Christian Ludwig, Philip Kestell, John R. Griffiths, Lloyd R. Kelland, Simon P. Robinson
Published 2006-03-01

Single Dose of the Antivascular Agent, ZD6126 (N-Acetylcoichinol-O-Phosphate), Reduces Perfusion for at Least 96 Hours in the GH3 Prolactinoma Rat Tumor Model

by Dominick J.O. McIntyre, Simon P. Robinson, Franklyn A. Howe, John R. Griffiths, Anderson J. Ryan, David C. Blakey, Ian S. Peers, John C. Waterton
Published 2004-03-01

BCR-ABL affects STAT5A and STAT5B differentially.

by Michael Schaller-Schönitz, David Barzan, Andrew J K Williamson, John R Griffiths, Iris Dallmann, Karin Battmer, Arnold Ganser, Anthony D Whetton, Michaela Scherr, Matthias Eder
Published 2014-01-01

Acute Tumor Response to ZD6126 Assessed by Intrinsic Susceptibility Magnetic Resonance Imaging

by Simon P. Robinson, Tammy L. Kalber, Franklyn A. Howe, Dominick J.O. McIntyre, John R. Griffiths, David C. Blakey, Lynsey Whittaker, Anderson J. Ryan, John C. Waterton
Published 2005-05-01

Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of a Novel Histone Deacetylase Inhibitor, LAQ824, in Human Colon Carcinoma Cells and Xenografts

by Yuen-Li Chung, Helen Troy, Rebecca Kristeleit, Wynne Aherne, L. Elizabeth Jackson, Peter Atadja, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Mounia Beloueche-Babari
Published 2008-04-01

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.

by Andrew Pierce, Andrew Williamson, Ewa Jaworska, John R Griffiths, Sam Taylor, Michael Walker, Mark Aspinall-O'Dea, Elaine Spooncer, Richard D Unwin, Toryn Poolman, David Ray, Anthony D Whetton
Published 2012-01-01

Correction: Identification of Nuclear Protein Targets for Six Leukemogenic Tyrosine Kinases Governed by Post-Translational Regulation

by Andrew Pierce, Andrew Williamson, Ewa Jaworska, John R. Griffiths, Sam Taylor, Michael Walker, Mark Aspinall O’Dea, Elaine Spooncer, Richard D. Unwin, Toryn Poolman, David Ray, Anthony D. Whetton
Published 2013-01-01

Correction: Identification of Nuclear Protein Targets for Six Leukemogenic Tyrosine Kinases Governed by Post-Translational Regulation.

by Andrew Pierce, Andrew Williamson, Ewa Jaworska, John R. Griffiths, Sam Taylor, Michael Walker, Mark Aspinall O’Dea, Elaine Spooncer, Richard D. Unwin, Toryn Poolman, David Ray, Anthony D. Whetton
Published 2013-01-01

Effects of HIF-1𝛼 and HIF2𝛼 on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

by Swethajit Biswas, Helen Troy, Russell Leek, Yuen-Li Chung, Ji-liang Li, Raju R. Raval, Helen Turley, Kevin Gatter, Francesco Pezzella, John R. Griffiths, Marion Stubbs, Adrian L. Harris
Published 2010-01-01

Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects

by Petros A. Tyrakis, Marie E. Yurkovich, Marco Sciacovelli, Evangelia K. Papachristou, Hannah R. Bridges, Edoardo Gaude, Alexander Schreiner, Clive D’Santos, Judy Hirst, Juan Hernandez-Fernaud, Roger Springett, John R. Griffiths, Christian Frezza
Published 2017-10-01