Developmental Genes and Regulatory Proteins, Domains of Cognitive Impairment in Schizophrenia Spectrum Psychosis and Implications for Antipsychotic Drug Discovery: The Example of D...

by John L. Waddington, John L. Waddington, Xuechu Zhen, Colm M. P. O’Tuathaigh, Colm M. P. O’Tuathaigh
Published 2020-01-01

Constitutive and Conditional Mutant Mouse Models for Understanding Dopaminergic Regulation of Orofacial Movements: Emerging Insights and Challenges

by Katsunori Tomiyama, John Drago, John L. Waddington, Noriaki Koshikawa
Published 2012-01-01

Behavioural and Anatomical Characterization of Mutant Mice With Targeted Deletion of D1 Dopamine Receptor–Expressing Cells: Response to Acute Morphine

by Daniela Babovic, Luning Jiang, Satoshi Goto, Ilse Gantois, Günter Schütz, Andrew J. Lawrence, John L. Waddington, John Drago
Published 2013-01-01

Effects of hypoxia-induced neonatal seizures on acute hippocampal injury and later-life seizure susceptibility and anxiety-related behavior in mice

by Natalia Rodriguez-Alvarez, Eva M. Jimenez-Mateos, Mark Dunleavy, John L. Waddington, Geraldine B. Boylan, David C. Henshall
Published 2015-11-01

Central dopamine D2 receptors regulate plasma glucose levels in mice through autonomic nerves

by Hiroko Ikeda, Naomi Yonemochi, Risa Mikami, Manabu Abe, Meiko Kawamura, Rie Natsume, Kenji Sakimura, John L. Waddington, Junzo Kamei
Published 2020-12-01

Convulsant doses of a dopamine D1 receptor agonist result in Erk-dependent increases in Zif268 and Arc/Arg3.1 expression in mouse dentate gyrus.

by Giuseppe Gangarossa, Manuela Di Benedetto, Gerard J O'Sullivan, Mark Dunleavy, Cristina Alcacer, Alessandra Bonito-Oliva, David C Henshall, John L Waddington, Emmanuel Valjent, Gilberto Fisone
Published 2011-05-01

Mutation of Semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology.

by Annette E Rünker, Colm O'Tuathaigh, Mark Dunleavy, Derek W Morris, Graham E Little, Aiden P Corvin, Michael Gill, David C Henshall, John L Waddington, Kevin J Mitchell
Published 2011-01-01

Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells

by Luning Jiang, Claire O'Leary, Hyun Ah. Kim, Clare L. Parish, Jim Massalas, John L. Waddington, Michelle E. Ehrlich, Günter Schütz, Ilse Gantois, Andrew J. Lawrence, John Drago
Published 2015-04-01

Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells

by Hyun Ah. Kim, Luning Jiang, Heather Madsen, Clare L. Parish, Jim Massalas, Arthur Smardencas, Claire O'Leary, Ilse Gantois, Colm O'Tuathaigh, John L. Waddington, Michelle E. Ehrlich, Andrew J. Lawrence, John Drago
Published 2014-02-01

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

by Eilis Hannon, Emma L Dempster, Georgina Mansell, Joe Burrage, Nick Bass, Marc M Bohlken, Aiden Corvin, Charles J Curtis, David Dempster, Marta Di Forti, Timothy G Dinan, Gary Donohoe, Fiona Gaughran, Michael Gill, Amy Gillespie, Cerisse Gunasinghe, Hilleke E Hulshoff, Christina M Hultman, Viktoria Johansson, René S Kahn, Jaakko Kaprio, Gunter Kenis, Kaarina Kowalec, James MacCabe, Colm McDonald, Andrew McQuillin, Derek W Morris, Kieran C Murphy, Colette J Mustard, Igor Nenadic, Michael C O'Donovan, Diego Quattrone, Alexander L Richards, Bart PF Rutten, David St Clair, Sebastian Therman, Timothea Toulopoulou, Jim Van Os, John L Waddington, Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Patrick Sullivan, Evangelos Vassos, Gerome Breen, David Andrew Collier, Robin M Murray, Leonard S Schalkwyk, Jonathan Mill
Published 2021-02-01