Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis

by Jeffrey S. Mugridge, Ryan W. Tibble, Marcin Ziemniak, Jacek Jemielity, John D. Gross
Published 2018-03-01

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes.

by Natalia Sevillano, Evan M Green, Jörg Votteler, Dong Young Kim, Xuefeng Ren, Bei Yang, Xi Liu, André Luiz Lourenço, James H Hurley, Shauna Farr-Jones, John D Gross, Yifan Cheng, Charles S Craik
Published 2021-01-01

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

by David J Stanley, Koen Bartholomeeusen, David C Crosby, Dong Young Kim, Eunju Kwon, Linda Yen, Nathalie Caretta Cartozo, Ming Li, Stefanie Jäger, Jeremy Mason-Herr, Fumiaki Hayashi, Shigeyuki Yokoyama, Nevan J Krogan, Reuben S Harris, Boris Matija Peterlin, John D Gross
Published 2012-12-01

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.

by Jennifer M Binning, Amber M Smith, Judd F Hultquist, Charles S Craik, Nathalie Caretta Cartozo, Melody G Campbell, Lily Burton, Florencia La Greca, Michael J McGregor, Hai M Ta, Koen Bartholomeeusen, B Matija Peterlin, Nevan J Krogan, Natalia Sevillano, Yifan Cheng, John D Gross
Published 2018-01-01

Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity

by Joshua R. Kane, David J. Stanley, Judd F. Hultquist, Jeffrey R. Johnson, Nicole Mietrach, Jennifer M. Binning, Stefán R. Jónsson, Sarah Barelier, Billy W. Newton, Tasha L. Johnson, Kathleen E. Franks-Skiba, Ming Li, William L. Brown, Hörður I. Gunnarsson, Adalbjorg Adalbjornsdóttir, James S. Fraser, Reuben S. Harris, Valgerður Andrésdóttir, John D. Gross, Nevan J. Krogan
Published 2015-05-01