Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations

by Johanna Wanngren, Patricia Lara, Karin Öjemalm, Silvia Maioli, Nasim Moradi, Lu Chen, Lars O. Tjernberg, Johan Lundkvist, IngMarie Nilsson, Helena Karlström
Published 2014-01-01