Laminar flow substantially affects the morphology and functional phenotype of glomerular endothelial cells.

by Daan C 't Hart, Johan van der Vlag, Tom Nijenhuis
Published 2021-01-01

Acetylated Histones in Apoptotic Microparticles Drive the Formation of Neutrophil Extracellular Traps in Active Lupus Nephritis

by Nils Rother, Elmar Pieterse, Jelle Lubbers, Luuk Hilbrands, Johan van der Vlag
Published 2017-09-01

Neutrophils discriminate between lipopolysaccharides of different bacterial sources and selectively release neutrophil extracellular traps

by Elmar Pieterse, Nils Rother, Cansu Yanginlar, Luuk Hilbrands, Johan Van Der Vlag
Published 2016-11-01

Epigenetic patterns maintained in early Caenorhabditis elegans embryos can be established by gene activity in the parental germ cells.

by Jackelyn K Arico, David J Katz, Johan van der Vlag, William G Kelly
Published 2011-06-01

Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients

by Baranca Buijsers, Cansu Yanginlar, Marissa L. Maciej-Hulme, Quirijn de Mast, Johan van der Vlag
Published 2020-09-01

Ligation of alpha-dystroglycan on podocytes induces intracellular signaling: a new mechanism for podocyte effacement?

by Nils P J Vogtländer, Henk Jan Visch, Marinka A H Bakker, Jo H M Berden, Johan van der Vlag
Published 2009-06-01

Protein Expression Correlates Linearly with mRNA Dose over Up to Five Orders of Magnitude In Vitro and In Vivo

by Alexander H. van Asbeck, Jürgen Dieker, Rik Oude Egberink, Lennard van den Berg, Johan van der Vlag, Roland Brock
Published 2021-05-01

A low molecular weight heparin inhibits experimental metastasis in mice independently of the endothelial glycocalyx.

by Geerte L Van Sluis, Max Nieuwdorp, Pieter W Kamphuisen, Johan van der Vlag, Cornelis J F Van Noorden, C Arnold Spek
Published 2010-01-01

Direct Observation of Enhanced Nitric Oxide in a Murine Model of Diabetic Nephropathy.

by Margien G S Boels, Ernst E H van Faassen, M Cristina Avramut, Johan van der Vlag, Bernard M van den Berg, Ton J Rabelink
Published 2017-01-01

Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice.

by Theun de Groot, Lars Damen, Leanne Kosse, Mohammad Alsady, Rosalinda Doty, Ruben Baumgarten, Susan Sheehan, Johan van der Vlag, Ron Korstanje, Peter M T Deen
Published 2017-01-01

Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria.

by Marjolein Garsen, Angelique L Rops, Jinhua Li, Katrien van Beneden, Christiane van den Branden, Jo Hm Berden, Ton J Rabelink, Johan van der Vlag
Published 2016-01-01

Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

by Marloes Sol, Jan A. A. M. Kamps, Jacob van den Born, Marius C. van den Heuvel, Johan van der Vlag, Guido Krenning, Jan-Luuk Hillebrands
Published 2020-10-01

Autoantibodies against Modified Histone Peptides in SLE Patients Are Associated with Disease Activity and Lupus Nephritis.

by Jürgen Dieker, Jo H Berden, Marinka Bakker, Jean-Paul Briand, Sylviane Muller, Reinhard Voll, Christopher Sjöwall, Martin Herrmann, Luuk B Hilbrands, Johan van der Vlag
Published 2016-01-01

IL-1β Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene

by Dhivya Thiyagarajan, Hege L. Pedersen, Natalya Seredkina, Kjersti D. Horvei, Lorena Arranz, Ramon Sonneveld, Tom Nijenhuis, Johan van der Vlag, Ole P. Rekvig, Ole P. Rekvig
Published 2018-02-01

RNA Contaminates Glycosaminoglycans Extracted from Cells and Tissues.

by Jasper J van Gemst, Markus A Loeven, Mark J J de Graaf, Jo H M Berden, Ton J Rabelink, Cornelis H Smit, Johan van der Vlag
Published 2016-01-01

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury.

by Nuria Maicas, Johan van der Vlag, Janin Bublitz, Sandrine Florquin, Marinka Bakker-van Bebber, Charles A Dinarello, Vivienne Verweij, Roos Masereeuw, Leo A Joosten, Luuk B Hilbrands
Published 2017-01-01

Alternative Pathway Is Essential for Glomerular Complement Activation and Proteinuria in a Mouse Model of Membranous Nephropathy

by Wentian Luo, Wentian Luo, Florina Olaru, Florina Olaru, Jeffrey H. Miner, Laurence H. Beck, Johan van der Vlag, Joshua M. Thurman, Dorin-Bogdan Borza, Dorin-Bogdan Borza
Published 2018-06-01

Selective Binding of Heparin/Heparan Sulfate Oligosaccharides to Factor H and Factor H-Related Proteins: Therapeutic Potential for C3 Glomerulopathies

by Markus A. Loeven, Marissa L. Maciej-Hulme, Cansu Yanginlar, Melanie C. Hubers, Edwin Kellenbach, Mark de Graaf, Toin H. van Kuppevelt, Jack Wetzels, Ton J. Rabelink, Richard J. H. Smith, Johan van der Vlag
Published 2021-08-01

TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy.

by Julia M Hofstra, Marieke J H Coenen, Mascha M V A P Schijvenaars, Jo H M Berden, Johan van der Vlag, Lies H Hoefsloot, Nine V A M Knoers, Jack F M Wetzels, Tom Nijenhuis
Published 2014-01-01

Autoantibodies Recognizing Secondary NEcrotic Cells Promote Neutrophilic Phagocytosis and Identify Patients With Systemic Lupus Erythematosus

by Mona H. C. Biermann, Sebastian Boeltz, Elmar Pieterse, Jasmin Knopf, Jürgen Rech, Rostyslav Bilyy, Rostyslav Bilyy, Johan van der Vlag, Angela Tincani, Jörg H. W. Distler, Gerhard Krönke, Georg Andreas Schett, Martin Herrmann, Luis E. Muñoz
Published 2018-05-01