From Human Pluripotent Stem Cells to 3D Cardiac Microtissues: Progress, Applications and Challenges

by Mariana A. Branco, Joaquim M.S. Cabral, Maria Margarida Diogo
Published 2020-08-01

Stem Cell Bioprocessing and Manufacturing

by Joaquim M.S. Cabral, Cláudia Lobato da Silva, Maria Margarida Diogo
Published 2020-07-01

An appraisal of human mitochondrial DNA instability: new insights into the role of non-canonical DNA structures and sequence motifs.

by Pedro H Oliveira, Cláudia Lobato da Silva, Joaquim M S Cabral
Published 2013-01-01

Single-Use Bioreactors for Human Pluripotent and Adult Stem Cells: Towards Regenerative Medicine Applications

by Diogo E.S. Nogueira, Joaquim M.S. Cabral, Carlos A.V. Rodrigues
Published 2021-05-01

Bone Matrix Non-Collagenous Proteins in Tissue Engineering: Creating New Bone by Mimicking the Extracellular Matrix

by Marta S. Carvalho, Joaquim M. S. Cabral, Cláudia L. da Silva, Deepak Vashishth
Published 2021-03-01

Impact of Donor Age on the Osteogenic Supportive Capacity of Mesenchymal Stromal Cell-Derived Extracellular Matrix

by Marta S. Carvalho, Marta S. Carvalho, Laura Alves, Laura Alves, Isabel Bogalho, Isabel Bogalho, Joaquim M. S. Cabral, Joaquim M. S. Cabral, Cláudia L. da Silva, Cláudia L. da Silva
Published 2021-10-01

Multifactorial Modeling Reveals a Dominant Role of Wnt Signaling in Lineage Commitment of Human Pluripotent Stem Cells

by Tiago P. Dias, Tiago G. Fernandes, Maria Margarida Diogo, Joaquim M. S. Cabral
Published 2019-08-01

Towards Multi-Organoid Systems for Drug Screening Applications

by Cláudia C. Miranda, Tiago G. Fernandes, Maria Margarida Diogo, Joaquim M. S. Cabral
Published 2018-06-01

Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives

by Ana Rita Gomes, Tiago G. Fernandes, Joaquim M.S. Cabral, Maria Margarida Diogo
Published 2021-04-01

Magnetic stimulation of the angiogenic potential of mesenchymal stromal cells in vascular tissue engineering

by Ana C. Manjua, Joaquim M. S. Cabral, Carla A. M. Portugal, Frederico Castelo Ferreira
Published 2021-12-01

Magnetic Field Dynamic Strategies for the Improved Control of the Angiogenic Effect of Mesenchymal Stromal Cells

by Ana C. Manjua, Joaquim M. S. Cabral, Frederico Castelo Ferreira, Carla A. M. Portugal
Published 2021-06-01

New insights into the mechanisms of embryonic stem cell self-renewal under hypoxia: a multifactorial analysis approach.

by Hélder S C Barbosa, Tiago G Fernandes, Tiago P Dias, Maria Margarida Diogo, Joaquim M S Cabral
Published 2012-01-01

Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products

by Brian Lee, Breanna S. Borys, Michael S. Kallos, Carlos A. V. Rodrigues, Teresa P. Silva, Joaquim M. S. Cabral
Published 2020-03-01

Human mesenchymal stem cell expression program upon extended ex-vivo cultivation, as revealed by 2-DE-based quantitative proteomics.

by Andreia Madeira, Cláudia L da Silva, Francisco dos Santos, Emilio Camafeita, Joaquim M S Cabral, Isabel Sá-Correia
Published 2012-01-01

Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering

by Teresa P. Silva, João P. Cotovio, Evguenia Bekman, Maria Carmo-Fonseca, Joaquim M. S. Cabral, Tiago G. Fernandes
Published 2019-01-01

Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells

by André Branco, Sara Bucar, Jorge Moura-Sampaio, Carla Lilaia, Joaquim M. S. Cabral, Ana Fernandes-Platzgummer, Cláudia Lobato da Silva
Published 2020-09-01

Proliferation extent of CD34+ cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage...

by Javad Hatami, Pedro Z. Andrade, Denise Bacalhau, Fernando Cirurgião, Frederico Castelo Ferreira, Joaquim M.S. Cabral, Cláudia L. da Silva
Published 2014-12-01

Strategies for the expansion of human induced pluripotent stem cells as aggregates in single-use Vertical-Wheel™ bioreactors

by Diogo E. S. Nogueira, Carlos A. V. Rodrigues, Marta S. Carvalho, Cláudia C. Miranda, Yas Hashimura, Sunghoon Jung, Brian Lee, Joaquim M. S. Cabral
Published 2019-09-01

Defined Essential 8™ Medium and Vitronectin Efficiently Support Scalable Xeno-Free Expansion of Human Induced Pluripotent Stem Cells in Stirred Microcarrier Culture Systems.

by Sara M Badenes, Tiago G Fernandes, Cláudia S M Cordeiro, Shayne Boucher, David Kuninger, Mohan C Vemuri, Maria Margarida Diogo, Joaquim M S Cabral
Published 2016-01-01

Successful Use of Human AB Serum to Support the Expansion of Adipose Tissue-Derived Mesenchymal Stem/Stromal Cell in a Microcarrier-Based Platform

by Francisco Moreira, Amanda Mizukami, Lucas Eduardo Botelho de Souza, Joaquim M. S. Cabral, Cláudia L. da Silva, Dimas T. Covas, Kamilla Swiech, Kamilla Swiech
Published 2020-04-01