Evasion of the immune response by Trypanosoma cruzi during acute infection

by Mariana Santos Cardoso, João Luís Reis-Cunha, Daniella C. Bartholomeu
Published 2016-01-01

Experimental Selection of Paromomycin Resistance in <i>Leishmania donovani</i> Amastigotes Induces Variable Genomic Polymorphisms

by Sarah Hendrickx, João Luís Reis-Cunha, Sarah Forrester, Daniel C. Jeffares, Guy Caljon
Published 2021-07-01

Genetic Polymorphisms and Phenotypic Profiles of Sulfadiazine-Resistant and Sensitive Toxoplasma gondii Isolates Obtained from Newborns with Congenital Toxoplasmosis in Minas Gerai...

by Letícia Azevedo Silva, João Luís Reis-Cunha, Daniella Castanheira Bartholomeu, Ricardo Wagner Almeida Vítor
Published 2017-01-01

The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites

by Viviane Corrêa Santos, Antonio Edson Rocha Oliveira, Augusto César Broilo Campos, João Luís Reis-Cunha, Daniella Castanheira Bartholomeu, Santuza Maria Ribeiro Teixeira, Ana Paula C. A. Lima, Rafaela Salgado Ferreira
Published 2021-09-01

Detection of multiple circulating Leishmania species in Lutzomyia longipalpis in the city of Governador Valadares, southeastern Brazil.

by Mariana Santos Cardoso, Gabrielle Ariadine Bento, Laila Viana de Almeida, Joseane Camilla de Castro, João Luís Reis-Cunha, Vanessa de Araújo Barbosa, Cristian Ferreira de Souza, Reginaldo Peçanha Brazil, Hugo Oswaldo Valdivia, Daniella Castanheira Bartholomeu
Published 2019-01-01

Leishmania infantum recombinant kinesin degenerated derived repeat (rKDDR): A novel potential antigen for serodiagnosis of visceral leishmaniasis.

by Lucas Dhom-Lemos, Agostinho Gonçalves Viana, João Luis Reis Cunha, Mariana Santos Cardoso, Tiago Antônio Oliveira Mendes, Guilherme Rafael Gomide Pinheiro, Williane Fernanda Siqueira, Francisco Pereira Lobo, Leandro Freitas Teles, Lilian Lacerda Bueno, Silvio Fernando Guimarães-Carvalho, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara
Published 2019-01-01

Identification of strain-specific B-cell epitopes in Trypanosoma cruzi using genome-scale epitope prediction and high-throughput immunoscreening with peptide arrays.

by Tiago Antônio de Oliveira Mendes, João Luís Reis Cunha, Rodrigo de Almeida Lourdes, Gabriela Flávia Rodrigues Luiz, Lucas Dhom Lemos, Ana Rita Rocha dos Santos, Antônia Cláudia Jácome da Câmara, Lúcia Maria da Cunha Galvão, Caryn Bern, Robert H Gilman, Ricardo Toshio Fujiwara, Ricardo Tostes Gazzinelli, Daniella Castanheira Bartholomeu
Published 2013-01-01

Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU

by João Luís Reis-Cunha, Rodrigo P. Baptista, Gabriela F. Rodrigues-Luiz, Anderson Coqueiro-dos-Santos, Hugo O. Valdivia, Laila Viana de Almeida, Mariana Santos Cardoso, Daniella Alchaar D’Ávila, Fernando Hugo Cunha Dias, Ricardo Toshio Fujiwara, Lúcia M. C. Galvão, Egler Chiari, Gustavo Coutinho Cerqueira, Daniella C. Bartholomeu
Published 2018-11-01

Genome-wide screening and identification of new Trypanosoma cruzi antigens with potential application for chronic Chagas disease diagnosis.

by João Luís Reis-Cunha, Tiago Antônio de Oliveira Mendes, Rodrigo de Almeida Lourdes, Daihana Rodrigues dos Santos Ribeiro, Ricardo Andrez Machado-de-Avila, Maykon de Oliveira Tavares, Denise Silveira Lemos, Antônia Cláudia Jácome Câmara, Carlos Chavez Olórtegui, Marta de Lana, Lúcia Maria da Cunha Galvão, Ricardo Toshio Fujiwara, Daniella Castanheira Bartholomeu
Published 2014-01-01

DNA Topoisomerase 3α Is Involved in Homologous Recombination Repair and Replication Stress Response in Trypanosoma cruzi

by Héllida Marina Costa-Silva, Bruno Carvalho Resende, Adriana Castilhos Souza Umaki, Willian Prado, Marcelo Santos da Silva, Stela Virgílio, Andrea Mara Macedo, Sérgio Danilo Junho Pena, Erich Birelli Tahara, Luiz Ricardo Orsini Tosi, Maria Carolina Elias, Luciana Oliveira Andrade, João Luís Reis-Cunha, Glória Regina Franco, Stenio Perdigão Fragoso, Carlos Renato Machado
Published 2021-05-01

Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

by Carlos Talavera-López, Carlos Talavera-López, Louisa A. Messenger, Michael D. Lewis, Matthew Yeo, João Luís Reis-Cunha, Gabriel Machado Matos, Daniella C. Bartholomeu, José E. Calzada, Azael Saldaña, Juan David Ramírez, Felipe Guhl, Sofía Ocaña-Mayorga, Jaime A. Costales, Rodion Gorchakov, Kathryn Jones, Melissa S. Nolan, Santuza M. R. Teixeira, Hernán José Carrasco, Maria Elena Bottazzi, Peter J. Hotez, Kristy O. Murray, Mario J. Grijalva, Mario J. Grijalva, Barbara Burleigh, Edmundo C. Grisard, Michael A. Miles, Björn Andersson
Published 2021-03-01