Dynamics of p53: A Master Decider of Cell Fate

by Qingyin Luo, Jill M. Beaver, Yuan Liu, Zunzhen Zhang
Published 2017-02-01

An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract.

by Jill M Beaver, Yanhao Lai, Shantell J Rolle, Liwei Weng, Marc M Greenberg, Yuan Liu
Published 2018-01-01

Crosstalk between MSH2–MSH3 and polβ promotes trinucleotide repeat expansion during base excision repair

by Yanhao Lai, Helen Budworth, Jill M. Beaver, Nelson L. S. Chan, Zunzhen Zhang, Cynthia T. McMurray, Yuan Liu
Published 2016-08-01

Base excision repair of chemotherapeutically-induced alkylated DNA damage predominantly causes contractions of expanded GAA repeats associated with Friedreich's ataxia.

by Yanhao Lai, Jill M Beaver, Karla Lorente, Jonathan Melo, Shyama Ramjagsingh, Irina U Agoulnik, Zunzhen Zhang, Yuan Liu
Published 2014-01-01

Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a <i>de novo</i> DNA Methyltransferase

by Zhongliang Jiang, Yanhao Lai, Jill M. Beaver, Pawlos S. Tsegay, Ming-Lang Zhao, Julie K. Horton, Marco Zamora, Hayley L. Rein, Frank Miralles, Mohammad Shaver, Joshua D. Hutcheson, Irina Agoulnik, Samuel H. Wilson, Yuan Liu
Published 2020-01-01