Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase.

by Jessica W Luzwick, Edward A Nam, Runxiang Zhao, David Cortez
Published 2014-01-01

Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators

by Sarah R. Wessel, Kareem N. Mohni, Jessica W. Luzwick, Huzefa Dungrawala, David Cortez
Published 2019-09-01

p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways

by Sunetra Roy, Karl-Heinz Tomaszowski, Jessica W Luzwick, Soyoung Park, Jun Li, Maureen Murphy, Katharina Schlacher
Published 2018-01-01

A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments.

by Kareem N Mohni, Petria S Thompson, Jessica W Luzwick, Gloria G Glick, Christopher S Pendleton, Brian D Lehmann, Jennifer A Pietenpol, David Cortez
Published 2015-01-01