Differential effects on the miRNome of the treatment of human airway epithelial Calu-3 cells with peptide-nucleic acids (PNAs) targeting microRNAs miR-101-3p and miR-145-5p: Next g...

by Jessica Gasparello, Enrica Fabbri, Roberto Gambari, Alessia Finotti
Published 2021-04-01

Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology.

by Jessica Gasparello, Chiara Papi, Matteo Zurlo, Roberto Corradini, Roberto Gambari, Alessia Finotti
Published 2019-01-01

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

by Jessica Gasparello, Alex Manicardi, Alessandro Casnati, Roberto Corradini, Roberto Gambari, Alessia Finotti, Francesco Sansone
Published 2019-02-01

Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β039-thalassemia patients

by Lucia Carmela Cosenza, Jessica Gasparello, Nicola Romanini, Matteo Zurlo, Cristina Zuccato, Roberto Gambari, Alessia Finotti
Published 2021-06-01

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

by Jessica Gasparello, Enrica Fabbri, Nicoletta Bianchi, Giulia Breveglieri, Cristina Zuccato, Monica Borgatti, Roberto Gambari, Alessia Finotti
Published 2017-11-01

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae.

by Emiliano Altamura, Monica Borgatti, Alessia Finotti, Jessica Gasparello, Roberto Gambari, Mariangela Spinelli, Rosa Castaldo, Nicola Altamura
Published 2016-01-01

Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle

by Jessica Gasparello, Michela Lomazzi, Chiara Papi, Elisabetta D’Aversa, Francesco Sansone, Alessandro Casnati, Gaetano Donofrio, Roberto Gambari, Alessia Finotti
Published 2019-12-01

A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery

by Jessica Gasparello, Chiara Papi, Matteo Allegretti, Elena Giordani, Fabio Carboni, Settimio Zazza, Edoardo Pescarmona, Paolo Romania, Patrizio Giacomini, Chiara Scapoli, Roberto Gambari, Alessia Finotti
Published 2020-08-01

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) mRNA Enhances CFTR Expression...

by Shaiq Sultan, Andrea Rozzi, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Chiara Papi, Alessia Finotti, Ilaria Lampronti, Eva Reali, Giulio Cabrini, Roberto Gambari, Monica Borgatti
Published 2020-04-01

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)

by Jessica Gasparello, Matteo Allegretti, Elisa Tremante, Enrica Fabbri, Carla Azzurra Amoreo, Paolo Romania, Elisa Melucci, Katia Messana, Monica Borgatti, Patrizio Giacomini, Roberto Gambari, Alessia Finotti
Published 2018-06-01

A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (<i>CFTR</i>) Gene with the Possible Involvement of the CFTR...

by Anna Tamanini, Enrica Fabbri, Tiziana Jakova, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Alessia Finotti, Monica Borgatti, Ilaria Lampronti, Silvia Munari, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Published 2021-01-01

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells

by Enrica Fabbri, Anna Tamanini, Tiziana Jakova, Jessica Gasparello, Alex Manicardi, Roberto Corradini, Giuseppe Sabbioni, Alessia Finotti, Monica Borgatti, Ilaria Lampronti, Silvia Munari, Maria Cristina Dechecchi, Giulio Cabrini, Roberto Gambari
Published 2017-12-01

Enzymatic Spermine Metabolites Induce Apoptosis Associated with Increase of p53, caspase-3 and miR-34a in Both Neuroblastoma Cells, SJNKP and the N-Myc-Amplified Form IMR5

by Yuta Kanamori, Alessia Finotti, Laura Di Magno, Gianluca Canettieri, Tomoaki Tahara, Fabio Timeus, Antonio Greco, Paola Tirassa, Jessica Gasparello, Pasquale Fino, Carlo Maria Di Liegro, Patrizia Proia, Gabriella Schiera, Italia Di Liegro, Roberto Gambari, Enzo Agostinelli
Published 2021-07-01

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma

by Po Yee Chung, Pik Ling Lam, Yuanyuan Zhou, Jessica Gasparello, Alessia Finotti, Adriana Chilin, Giovanni Marzaro, Roberto Gambari, Zhaoxiang Bian, Wai Ming Kwok, Wai Yeung Wong, Xi Wang, Alfred King-yin Lam, Albert Sun-chi Chan, Xingshu Li, Jessica Yuen Wuen Ma, Chung Hin Chui, Kim Hung Lam, Johnny Cheuk On Tang
Published 2018-10-01