Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum.

by John B Patton, Sasisekhar Bennuru, Mark L Eberhard, Jessica A Hess, April Torigian, Sara Lustigman, Thomas B Nutman, David Abraham
Published 2018-12-01

Strongyloides stercoralis and HTLV-1 coinfection in CD34+ cord blood stem cell humanized mice: Alteration of cytokine responses and enhancement of larval growth.

by Lauren E Springer, John B Patton, Tingting Zhan, Arnold B Rabson, Hsin-Ching Lin, Tim Manser, James B Lok, Jessica A Hess, David Abraham
Published 2021-07-01

Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans.

by Parakkal Jovvian George, Jessica A Hess, Sonia Jain, John B Patton, Tingting Zhan, Nancy Tricoche, Bin Zhan, Maria Elena Bottazzi, Peter J Hotez, David Abraham, Sara Lustigman
Published 2019-09-01

The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice.

by Jessica A Hess, Bin Zhan, April R Torigian, John B Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J Hotez, Thomas R Klei, Sara Lustigman, David Abraham
Published 2016-07-01

Onchocerca volvulus bivalent subunit vaccine induces protective immunity in genetically diverse collaborative cross recombinant inbred intercross mice

by Nathan M. Ryan, Jessica A. Hess, Fernando Pardo-Manuel de Villena, Benjamin E. Leiby, Ayako Shimada, Lei Yu, Amir Yarmahmoodi, Nikolai Petrovsky, Bin Zhan, Maria Elena Bottazzi, Benjamin L. Makepeace, Sara Lustigman, David Abraham
Published 2021-01-01