Ikaros cooperates with Notch activation and antagonizes TGFβ signaling to promote pDC development.

by Jérôme Mastio, Célestine Simand, Giovanni Cova, Philippe Kastner, Susan Chan, Peggy Kirstetter
Published 2018-07-01

Higher Incidence of B Cell Malignancies in Primary Immunodeficiencies: A Combination of Intrinsic Genomic Instability and Exocytosis Defects at the Immunological Synapse

by Jérôme Mastio, Mezida B. Saeed, Hannah Wurzer, Max Krecke, Lisa S. Westerberg, Clément Thomas
Published 2020-11-01

Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remo...

by Hannah Wurzer, Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Max Krecke, Andrea Michela Biolato, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas
Published 2021-05-01

PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

by Gaurav Sharma, Rani Ojha, Estela Noguera-Ortega, Vito W. Rebecca, John Attanasio, Shujing Liu, Shengfu Piao, Jennifer J. Lee, Michael C. Nicastri, Sandra L. Harper, Amruta Ronghe, Vaibhav Jain, Jeffrey D. Winkler, David W. Speicher, Jerome Mastio, Phyllis A. Gimotty, Xiaowei Xu, E. John Wherry, Dmitry I. Gabrilovich, Ravi K. Amaravadi
Published 2020-09-01