Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection

by Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M. Fleckenstein, James B. Kaper, Mark Donowitz
Published 2020-11-01

Evaluation of a Live Attenuated <i>S. sonnei</i> Vaccine Strain in the Human Enteroid Model

by Giulia Pilla, Tao Wu, Christen Grassel, Jonathan Moon, Jennifer Foulke-Abel, Christoph M. Tang, Eileen M. Barry
Published 2021-08-01

Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid MonolayersSummary

by Jianyi Yin, Chung-Ming Tse, Leela Rani Avula, Varsha Singh, Jennifer Foulke-Abel, Hugo R. de Jonge, Mark Donowitz
Published 2018-01-01

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived ColonoidsSummary

by Julie In, Jennifer Foulke-Abel, Nicholas C. Zachos, Anne-Marie Hansen, James B. Kaper, Harris D. Bernstein, Marc Halushka, Sarah Blutt, Mary K. Estes, Mark Donowitz, Olga Kovbasnjuk
Published 2016-01-01

Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

by C. Ming Tse, Julie G. In, Jianyi Yin, Mark Donowitz, Michele Doucet, Jennifer Foulke-Abel, Fernando Ruiz-Perez, James P. Nataro, Nicholas C. Zachos, James B. Kaper, Olga Kovbasnjuk
Published 2018-09-01

Serine protease EspP from enterohemorrhagic Escherichia coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium.

by Julie In, Valeriy Lukyanenko, Jennifer Foulke-Abel, Ann L Hubbard, Michael Delannoy, Anne-Marie Hansen, James B Kaper, Nadia Boisen, James P Nataro, Chengru Zhu, Edgar C Boedeker, Jorge A Girón, Olga Kovbasnjuk
Published 2013-01-01