A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study.

by Amy E Armstrong, Samantha Gadd, Vicki Huff, Daniela S Gerhard, Jeffrey S Dome, Elizabeth J Perlman
Published 2018-01-01

TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia.

by Mariana Maschietto, Richard D Williams, Tasnim Chagtai, Sergey D Popov, Neil J Sebire, Gordan Vujanic, Elizabeth Perlman, James R Anderson, Paul Grundy, Jeffrey S Dome, Kathy Pritchard-Jones
Published 2014-01-01

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

by Samantha Gadd, Vicki Huff, Chiang-Ching Huang, E. Cristy Ruteshouser, Jeffrey S. Dome, Paul E. Grundy, Norman Breslow, Lawrence Jennings, Daniel M. Green, J. Bruce Beckwith, Elizabeth J. Perlman
Published 2012-08-01

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

by Andrew J. Murphy, Xiang Chen, Emilia M. Pinto, Justin S. Williams, Michael R. Clay, Stanley B. Pounds, Xueyuan Cao, Lei Shi, Tong Lin, Geoffrey Neale, Christopher L. Morton, Mary A. Woolard, Heather L. Mulder, Hyea Jin Gil, Jerold E. Rehg, Catherine A. Billups, Matthew L. Harlow, Jeffrey S. Dome, Peter J. Houghton, John Easton, Jinghui Zhang, Rani E. George, Gerard P. Zambetti, Andrew M. Davidoff
Published 2019-12-01