Graphical approach to model reduction for nonlinear biochemical networks.

by David O Holland, Nicholas C Krainak, Jeffrey J Saucerman
Published 2011-01-01

Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy.

by Ali Khalilimeybodi, Alexander M Paap, Steven L M Christiansen, Jeffrey J Saucerman
Published 2020-12-01

Mechano-chemo signaling interactions modulate matrix production by cardiac fibroblasts

by Jesse D. Rogers, Jeffrey W. Holmes, Jeffrey J. Saucerman, William J. Richardson
Published 2021-06-01

Predictive model identifies key network regulators of cardiomyocyte mechano-signaling.

by Philip M Tan, Kyle S Buchholz, Jeffrey H Omens, Andrew D McCulloch, Jeffrey J Saucerman
Published 2017-11-01

Multiscale Coupling of an Agent-Based Model of Tissue Fibrosis and a Logic-Based Model of Intracellular Signaling

by S. Michaela Rikard, Thomas L. Athey, Anders R. Nelson, Steven L. M. Christiansen, Jia-Jye Lee, Jeffrey W. Holmes, Jeffrey W. Holmes, Jeffrey W. Holmes, Shayn M. Peirce, Shayn M. Peirce, Jeffrey J. Saucerman, Jeffrey J. Saucerman
Published 2019-12-01

Network model‐based screen for FDA‐approved drugs affecting cardiac fibrosis

by Angela C. Zeigler, Anirudha S. Chandrabhatla, Steven L. Christiansen, Anders R. Nelson, Jeffrey W. Holmes, Jeffrey J. Saucerman
Published 2021-04-01

High content analysis identifies unique morphological features of reprogrammed cardiomyocytes

by Matthew D. Sutcliffe, Philip M. Tan, Antonio Fernandez-Perez, Young-Jae Nam, Nikhil V. Munshi, Jeffrey J. Saucerman
Published 2018-01-01

Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics

by Jaehee V. Shim, Bryan Chun, Johan G. C. van Hasselt, Marc R. Birtwistle, Jeffrey J. Saucerman, Eric A. Sobie
Published 2017-09-01

Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

by Rhianna C. Laker, Joshua C. Drake, Rebecca J. Wilson, Vitor A. Lira, Bevan M. Lewellen, Karen A. Ryall, Carleigh C. Fisher, Mei Zhang, Jeffrey J. Saucerman, Laurie J. Goodyear, Mondira Kundu, Zhen Yan
Published 2017-09-01