Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice

by Benoit Roch, Benoit Roch, Vincent Abramowski, Vincent Abramowski, Julie Chaumeil, Jean-Pierre de Villartay, Jean-Pierre de Villartay
Published 2019-03-01

CD8 Memory Cells Develop Unique DNA Repair Mechanisms Favoring Productive Division.

by Alessia Galgano, Aleksandr Barinov, Florence Vasseur, Jean-Pierre de Villartay, Benedita Rocha
Published 2015-01-01

DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF.

by Rémy Bétous, Théo Goullet de Rugy, Alessandra Luiza Pelegrini, Sophie Queille, Jean-Pierre de Villartay, Jean-Sébastien Hoffmann
Published 2018-07-01

Impaired replication stress response in cells from immunodeficiency patients carrying Cernunnos/XLF mutations.

by Michal Schwartz, Yifat S Oren, Assaf C Bester, Ayelet Rahat, Ruthy Sfez, Shlomo Yitzchaik, Jean-Pierre de Villartay, Batsheva Kerem
Published 2009-01-01

Severe combined immunodeficiency caused by a new homozygous RAG1 mutation with progressive encephalopathy

by Nivedita Dhingra, Satya Prakash Yadav, Jean-Pierre de Villartay, Capucine Picard, RK Sabharwal, Veronique Dinand, Samarjit Singh Ghuman, Anupam Sachdeva
Published 2014-03-01

RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair

by Chloé Lescale, Vincent Abramowski, Marie Bedora-Faure, Valentine Murigneux, Gabriella Vera, David B. Roth, Patrick Revy, Jean-Pierre de Villartay, Ludovic Deriano
Published 2016-02-01

Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2

by Thomas Barthlott, Adam E. Handel, Hong Ying Teh, Rushika C. Wirasinha, Katrin Hafen, Saulius Žuklys, Benoit Roch, Stuart H. Orkin, Jean-Pierre de Villartay, Stephen R. Daley, Georg A. Holländer
Published 2021-06-01

Biosafety Studies of a Clinically Applicable Lentiviral Vector for the Gene Therapy of Artemis-SCID

by Sabine Charrier, Chantal Lagresle-Peyrou, Valentina Poletti, Michael Rothe, Grégory Cédrone, Bernard Gjata, Fulvio Mavilio, Alain Fischer, Axel Schambach, Jean-Pierre de Villartay, Marina Cavazzana, Salima Hacein-Bey-Abina, Anne Galy
Published 2019-12-01

Impaired telomere integrity and rRNA biogenesis in PARN‐deficient patients and knock‐out models

by Maname Benyelles, Harikleia Episkopou, Marie‐Françoise O'Donohue, Laëtitia Kermasson, Pierre Frange, Florian Poulain, Fatma Burcu Belen, Meltem Polat, Christine Bole‐Feysot, Francina Langa‐Vives, Pierre‐Emmanuel Gleizes, Jean‐Pierre deVillartay, Isabelle Callebaut, Anabelle Decottignies, Patrick Revy
Published 2019-07-01

Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signaling.

by Rajesh Jayachandran, Xiaolong Liu, Somdeb Bosedasgupta, Philipp Müller, Chun-Lei Zhang, Despina Moshous, Vera Studer, Jacques Schneider, Christel Genoud, Catherine Fossoud, Frédéric Gambino, Malik Khelfaoui, Christian Müller, Deborah Bartholdi, Helene Rossez, Michael Stiess, Xander Houbaert, Rolf Jaussi, Daniel Frey, Richard A Kammerer, Xavier Deupi, Jean-Pierre de Villartay, Andreas Lüthi, Yann Humeau, Jean Pieters
Published 2014-03-01

Somatic genetic rescue of a germline ribosome assembly defect

by Shengjiang Tan, Laëtitia Kermasson, Christine Hilcenko, Vasileios Kargas, David Traynor, Ahmed Z. Boukerrou, Norberto Escudero-Urquijo, Alexandre Faille, Alexis Bertrand, Maxim Rossmann, Beatriz Goyenechea, Li Jin, Jonathan Moreil, Olivier Alibeu, Blandine Beaupain, Christine Bôle-Feysot, Stefano Fumagalli, Sophie Kaltenbach, Jean-Alain Martignoles, Cécile Masson, Patrick Nitschké, Mélanie Parisot, Aurore Pouliet, Isabelle Radford-Weiss, Frédéric Tores, Jean-Pierre de Villartay, Mohammed Zarhrate, Ai Ling Koh, Kong Boo Phua, Bruno Reversade, Peter J. Bond, Christine Bellanné-Chantelot, Isabelle Callebaut, François Delhommeau, Jean Donadieu, Alan J. Warren, Patrick Revy
Published 2021-08-01