Reactivity of 3-Ethoxycarbonyl Isoquinolinium Salts Towards Various Nucleophilic Reagents: Applications to the Synthesis of New 1,2-Dihydroisoquinoline-3-carboxylates

by Jean Pierre Bazureau, Mohamed Ameziane Aït Amer Meziane
Published 2002-02-01

Task-specific ionic liquid technology applied to the synthesis of Biginelli 3,4-dihydropyrimidine-2(1H)-ones: A three-component condensation protocol based on ionic liquid phase bo...

by Jean Christophe Legeay, Jean Jacques Vanden Eynde, Loic Toupet, Jean Pierre Bazureau
Published 2006-09-01

A Practical Approach to New (5Z) 2-Alkylthio-5-arylmethylene-1-methyl-1,5-dihydro-4H-imidazol-4-one Derivatives

by Jean Pierre Bazureau, Laurent Meijer, Olivier Lozach, Ludovic Paquin, Khadidja Bourahla, François Carreaux
Published 2011-08-01

A Convenient Four-Step Synthesis of 1-{β-[3-(4-Methoxy-phenyl)Propoxy]-4-Methoxyphenethyl}-1H-Imidazole Hydrochloride as a Probing Tool for SOCE Assays

by Camille D. Dago, Estelle Messé, Olivier Mignen, Christophe Brigaudeau, Yves-Alain Békro, Jean-Pierre Bazureau
Published 2016-09-01

Reactivity of 2-Thiohydantoins Towards Various Electrophilic Reagents: Applications to the Synthesis of New 2-Ylidene-3,5-dihydro-4H-imidazol-4-ones.

by Jean Pierre Bazureau, François Carreaux, Jean-René Chérouvrier
Published 2004-09-01

Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors

by Camille D. Dago, Paul Le Maux, Thierry Roisnel, Christophe Brigaudeau, Yves-Alain Bekro, Olivier Mignen, Jean-Pierre Bazureau
Published 2018-03-01

Microwave-Assisted Condensation Reactions of Acetophenone Derivatives and Activated Methylene Compounds with Aldehydes Catalyzed by Boric Acid under Solvent-Free Conditions

by Elodie Brun, Abdelmounaim Safer, François Carreaux, Khadidja Bourahla, Jean-Martial L'helgoua'ch, Jean-Pierre Bazureau, Jose Manuel Villalgordo
Published 2015-06-01

Microwave assisted practical synthesis of 4-imino-3-phenyl-3,4-dihydro-1H-chromeno[2,3-d]pyrimidine-2(5H)-thione derivatives and exploration of their biological activities

by Ali Bouattour, Mehdi Fakhfakh, Souhir Abid, Ludovic Paquin, Rémy Le Guével, Anne Corlu, Sandrine Ruchaud, Stéphane Bach, Houcine Ammar, Jean-Pierre Bazureau
Published 2017-05-01

Synthetic Development of New 3-(4-Arylmethylamino)butyl-5-arylidene-rhodanines under Microwave Irradiation and Their Effects on Tumor Cell Lines and against Protein Kinases

by Camille Déliko Dago, Christelle N´ta Ambeu, Wacothon-Karime Coulibaly, Yves-Alain Békro, Janat Mamyrbékova, Audrey Defontaine, Blandine Baratte, Stéphane Bach, Sandrine Ruchaud, Rémy Le Guével, Myriam Ravache, Anne Corlu, Jean-Pierre Bazureau
Published 2015-07-01

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A

by Thu Lan Nguyen, Arnaud Duchon, Antigoni Manousopoulou, Nadège Loaëc, Benoît Villiers, Guillaume Pani, Meltem Karatas, Anna E. Mechling, Laura-Adela Harsan, Emmanuelle Limanton, Jean-Pierre Bazureau, François Carreaux, Spiros D. Garbis, Laurent Meijer, Yann Herault
Published 2018-09-01

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

by Benoît Souchet, Mickael Audrain, Jean Marie Billard, Julien Dairou, Romain Fol, Nicola Salvatore Orefice, Satoru Tada, Yuchen Gu, Gaelle Dufayet-Chaffaud, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau, Sandro Alves, Laurent Meijer, Nathalie Janel, Jérôme Braudeau, Nathalie Cartier
Published 2019-03-01

Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases

by Nadège Loaëc, Eletta Attanasio, Benoît Villiers, Emilie Durieu, Tania Tahtouh, Morgane Cam, Rohan A. Davis, Aline Alencar, Mélanie Roué, Marie-Lise Bourguet-Kondracki, Peter Proksch, Emmanuelle Limanton, Solène Guiheneuf, François Carreaux, Jean-Pierre Bazureau, Michelle Klautau, Laurent Meijer
Published 2017-10-01