Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells.

by Jay E Johnson, F Brad Johnson
Published 2014-01-01

Extension of Cellular Lifespan by Methionine Restriction Involves Alterations in Central Carbon Metabolism and Is Mitophagy-Dependent

by Jason D. Plummer, Jay E. Johnson
Published 2019-11-01

The integrated stress response in budding yeast lifespan extension

by Spike D.L. Postnikoff, Jay E. Johnson, Jessica K. Tyler
Published 2017-10-01

Selenium supplementation inhibits IGF-1 signaling and confers methionine restriction-like healthspan benefits to mice

by Jason D Plummer, Spike DL Postnikoff, Jessica K Tyler, Jay E Johnson
Published 2021-03-01