Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.

by Chae Kim, Tracy Haldiman, Yvonne Cohen, Wei Chen, Janis Blevins, Man-Sun Sy, Mark Cohen, Jiri G Safar
Published 2011-09-01

Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C).

by Chae Kim, Tracy Haldiman, Krystyna Surewicz, Yvonne Cohen, Wei Chen, Janis Blevins, Man-Sun Sy, Mark Cohen, Qingzhong Kong, Glenn C Telling, Witold K Surewicz, Jiri G Safar
Published 2012-01-01