Threshold-free population analysis identifies larger DRG neurons to respond stronger to NGF stimulation.

by Christine Andres, Jan Hasenauer, Frank Allgower, Tim Hucho
Published 2012-01-01

Scalable Parameter Estimation for Genome-Scale Biochemical Reaction Networks.

by Fabian Fröhlich, Barbara Kaltenbacher, Fabian J Theis, Jan Hasenauer
Published 2017-01-01

ODE constrained mixture modelling: a method for unraveling subpopulation structures and dynamics.

by Jan Hasenauer, Christine Hasenauer, Tim Hucho, Fabian J Theis
Published 2014-07-01

Benchmarking of numerical integration methods for ODE models of biological systems

by Philipp Städter, Yannik Schälte, Leonard Schmiester, Jan Hasenauer, Paul L. Stapor
Published 2021-01-01

CERENA: ChEmical REaction Network Analyzer--A Toolbox for the Simulation and Analysis of Stochastic Chemical Kinetics.

by Atefeh Kazeroonian, Fabian Fröhlich, Andreas Raue, Fabian J Theis, Jan Hasenauer
Published 2016-01-01

Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion.

by Fabian Fröhlich, Philipp Thomas, Atefeh Kazeroonian, Fabian J Theis, Ramon Grima, Jan Hasenauer
Published 2016-07-01

Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis

by Lisa Bast, Filippo Calzolari, Michael K. Strasser, Jan Hasenauer, Fabian J. Theis, Jovica Ninkovic, Carsten Marr
Published 2018-12-01

COVID-19 outbreak in Wuhan demonstrates the limitations of publicly available case numbers for epidemiological modeling

by Elba Raimúndez, Erika Dudkin, Jakob Vanhoefer, Emad Alamoudi, Simon Merkt, Lara Fuhrmann, Fan Bai, Jan Hasenauer
Published 2021-03-01

HCV Spread Kinetics Reveal Varying Contributions of Transmission Modes to Infection Dynamics

by Karina Durso-Cain, Peter Kumberger, Yannik Schälte, Theresa Fink, Harel Dahari, Jan Hasenauer, Susan L. Uprichard, Frederik Graw
Published 2021-07-01

Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines.

by Elba Raimúndez, Simone Keller, Gwen Zwingenberger, Karolin Ebert, Sabine Hug, Fabian J Theis, Dieter Maier, Birgit Luber, Jan Hasenauer
Published 2020-03-01

Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysi...

by Simone Keller, Julia Kneissl, Verena Grabher-Meier, Stefan Heindl, Jan Hasenauer, Dieter Maier, Julian Mattes, Peter Winter, Birgit Luber
Published 2017-12-01

Effects of trastuzumab and afatinib on kinase activity in gastric cancer cell lines

by Simone Keller, Gwen Zwingenberger, Karolin Ebert, Jan Hasenauer, Jacqueline Wasmuth, Dieter Maier, Ivonne Haffner, Katrin Schierle, Gregor Weirich, Birgit Luber
Published 2018-04-01

Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells

by Lorenz Adlung, Paul Stapor, Christian Tönsing, Leonard Schmiester, Luisa E. Schwarzmüller, Lena Postawa, Dantong Wang, Jens Timmer, Ursula Klingmüller, Jan Hasenauer, Marcel Schilling
Published 2021-08-01

Determining the effects of trastuzumab, cetuximab and afatinib by phosphoprotein, gene expression and phenotypic analysis in gastric cancer cell lines

by Karolin Ebert, Gwen Zwingenberger, Elena Barbaria, Simone Keller, Corinna Heck, Rouven Arnold, Vanessa Hollerieth, Julian Mattes, Robert Geffers, Elba Raimúndez, Jan Hasenauer, Birgit Luber
Published 2020-10-01

Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes

by Constance Alabert, Carolin Loos, Moritz Voelker-Albert, Simona Graziano, Ignasi Forné, Nazaret Reveron-Gomez, Lea Schuh, Jan Hasenauer, Carsten Marr, Axel Imhof, Anja Groth
Published 2020-01-01

Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes

by Wataru Fujii, Theodore S. Kapellos, Kevin Baßler, Kristian Händler, Lisa Holsten, Rainer Knoll, Stefanie Warnat-Herresthal, Marie Oestreich, Emily R. Hinkley, Jan Hasenauer, Carmen Pizarro, Christoph Thiele, Anna C. Aschenbrenner, Thomas Ulas, Dirk Skowasch, Joachim L. Schultze
Published 2021-09-01

PEtab-Interoperable specification of parameter estimation problems in systems biology.

by Leonard Schmiester, Yannik Schälte, Frank T Bergmann, Tacio Camba, Erika Dudkin, Janine Egert, Fabian Fröhlich, Lara Fuhrmann, Adrian L Hauber, Svenja Kemmer, Polina Lakrisenko, Carolin Loos, Simon Merkt, Wolfgang Müller, Dilan Pathirana, Elba Raimúndez, Lukas Refisch, Marcus Rosenblatt, Paul L Stapor, Philipp Städter, Dantong Wang, Franz-Georg Wieland, Julio R Banga, Jens Timmer, Alejandro F Villaverde, Sven Sahle, Clemens Kreutz, Jan Hasenauer, Daniel Weindl
Published 2021-01-01

Prevalence and Risk Factors of Infection in the Representative COVID-19 Cohort Munich

by Michael Pritsch, Katja Radon, Abhishek Bakuli, Ronan Le Gleut, Laura Olbrich, Jessica Michelle Guggenbüehl Noller, Elmar Saathoff, Noemi Castelletti, Mercè Garí, Peter Pütz, Yannik Schälte, Turid Frahnow, Roman Wölfel, Camilla Rothe, Michel Pletschette, Dafni Metaxa, Felix Forster, Verena Thiel, Friedrich Rieß, Maximilian Nikolaus Diefenbach, Günter Fröschl, Jan Bruger, Simon Winter, Jonathan Frese, Kerstin Puchinger, Isabel Brand, Inge Kroidl, Jan Hasenauer, Christiane Fuchs, Andreas Wieser, Michael Hoelscher, on behalf of the KoCo19 study group
Published 2021-03-01

From first to second wave: follow-up of the prospective COVID-19 cohort (KoCo19) in Munich (Germany)

by Katja Radon, Abhishek Bakuli, Peter Pütz, Ronan Le Gleut, Jessica Michelle Guggenbuehl Noller, Laura Olbrich, Elmar Saathoff, Mercè Garí, Yannik Schälte, Turid Frahnow, Roman Wölfel, Michael Pritsch, Camilla Rothe, Michel Pletschette, Raquel Rubio-Acero, Jessica Beyerl, Dafni Metaxa, Felix Forster, Verena Thiel, Noemi Castelletti, Friedrich Rieß, Maximilian N. Diefenbach, Günter Fröschl, Jan Bruger, Simon Winter, Jonathan Frese, Kerstin Puchinger, Isabel Brand, Inge Kroidl, Andreas Wieser, Michael Hoelscher, Jan Hasenauer, Christiane Fuchs, the KoCo19 study group
Published 2021-09-01