Vestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor.

by Jamie T Bridgham, June Keay, Eric A Ortlund, Joseph W Thornton
Published 2014-01-01

Evolution of a new function by degenerative mutation in cephalochordate steroid receptors.

by Jamie T Bridgham, Justine E Brown, Adriana Rodríguez-Marí, Julian M Catchen, Joseph W Thornton
Published 2008-09-01

Coevolution of the Toll-Like Receptor 4 Complex with Calgranulins and Lipopolysaccharide

by Andrea N. Loes, Andrea N. Loes, Jamie T. Bridgham, Michael J. Harms, Michael J. Harms
Published 2018-02-01

Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor.

by Jamie T Bridgham, Geeta N Eick, Claire Larroux, Kirti Deshpande, Michael J Harms, Marie E A Gauthier, Eric A Ortlund, Bernard M Degnan, Joseph W Thornton
Published 2010-10-01