The biology and role of CD44 in cancer progression: therapeutic implications

by Chen Chen, Shujie Zhao, Anand Karnad, James W. Freeman
Published 2018-05-01

Oncogenic K-Ras and loss of Smad4 mediate invasion by activating an EGFR/NF-κB Axis that induces expression of MMP9 and uPA in human pancreas progenitor cells.

by Alakesh Bera, Shujie Zhao, Lin Cao, Paul J Chiao, James W Freeman
Published 2013-01-01

A miRNA signature of chemoresistant mesenchymal phenotype identifies novel molecular targets associated with advanced pancreatic cancer.

by Alakesh Bera, Kolaparthi VenkataSubbaRao, Muthu Saravanan Manoharan, Ping Hill, James W Freeman
Published 2014-01-01

Cooperativity of oncogenic K-ras and downregulated p16/INK4A in human pancreatic tumorigenesis.

by Zhe Chang, Huaiqiang Ju, Jianhua Ling, Zhuonan Zhuang, Zhongkui Li, Huamin Wang, Jason B Fleming, James W Freeman, Dihua Yu, Peng Huang, Paul J Chiao
Published 2014-01-01