Lipids, Lipoproteins, and Age-Related Macular Degeneration

by Katayoon B. Ebrahimi, James T. Handa
Published 2011-01-01

Chronic cigarette smoke causes oxidative damage and apoptosis to retinal pigmented epithelial cells in mice.

by Masashi Fujihara, Norihiro Nagai, Thomas E Sussan, Shyam Biswal, James T Handa
Published 2008-09-01

Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.

by Joel C Sunshine, Sarah B Sunshine, Imran Bhutto, James T Handa, Jordan J Green
Published 2012-01-01

Changes in retinal pigment epithelium related to cigarette smoke: possible relevance to smoking as a risk factor for age-related macular degeneration.

by Ai Ling Wang, Thomas J Lukas, Ming Yuan, Nga Du, James T Handa, Arthur H Neufeld
Published 2009-01-01

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

by James T. Handa, Cathy Bowes Rickman, Andrew D. Dick, Michael B. Gorin, Joan W. Miller, Cynthia A. Toth, Marius Ueffing, Marco Zarbin, Lindsay A. Farrer
Published 2019-07-01

Examining the effects of cigarette smoke on mouse lens through a multi OMIC approach

by Shahid Y. Khan, Muhammad Ali, Yura Jang, Taekyung Ryu, Andrew J. Schwab, Brian O. Ingram, Peter H. Cable, Chan Hyun Na, James T. Handa, S. Amer Riazuddin
Published 2021-09-01

Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation.

by Laura Asnaghi, Michael H Lin, Kah Suan Lim, Kah Jing Lim, Arushi Tripathy, Murilo Wendeborn, Shannath L Merbs, James T Handa, Akrit Sodhi, Eli E Bar, Charles G Eberhart
Published 2014-01-01

T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.

by Fernando Cruz-Guilloty, Ali M Saeed, Stephanie Duffort, Marisol Cano, Katayoon B Ebrahimi, Asha Ballmick, Yaohong Tan, Hua Wang, James M Laird, Robert G Salomon, James T Handa, Victor L Perez
Published 2014-01-01

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

by Jie Wang, Cristina Zibetti, Peng Shang, Srinivasa R. Sripathi, Pingwu Zhang, Marisol Cano, Thanh Hoang, Shuli Xia, Hongkai Ji, Shannath L. Merbs, Donald J. Zack, James T. Handa, Debasish Sinha, Seth Blackshaw, Jiang Qian
Published 2018-04-01

βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells

by Peng Shang, Nadezda Stepicheva, Kenneth Teel, Austin McCauley, Christopher Scott Fitting, Stacey Hose, Rhonda Grebe, Meysam Yazdankhah, Sayan Ghosh, Haitao Liu, Anastasia Strizhakova, Joseph Weiss, Imran A. Bhutto, Gerard A. Lutty, Ashwath Jayagopal, Jiang Qian, José-Alain Sahel, J. Samuel Zigler, James T. Handa, Yuri Sergeev, Raju V. S. Rajala, Simon Watkins, Debasish Sinha
Published 2021-07-01

βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity

by Sayan Ghosh, Haitao Liu, Meysam Yazdankhah, Nadezda Stepicheva, Peng Shang, Tanuja Vaidya, Stacey Hose, Urvi Gupta, Michael Joseph Calderon, Ming-Wen Hu, Archana Padmanabhan Nair, Joseph Weiss, Christopher S. Fitting, Imran A. Bhutto, Santosh Gopi Krishna Gadde, Naveen Kumar Naik, Chaitra Jaydev, Gerard A. Lutty, James T. Handa, Ashwath Jayagopal, Jiang Qian, José-Alain Sahel, Dhivyaa Rajasundaram, Yuri Sergeev, J. Samuel Zigler, Swaminathan Sethu, Simon Watkins, Arkasubhra Ghosh, Debasish Sinha
Published 2021-02-01