Reduced CD5 on CD8+ T Cells in Tumors but Not Lymphoid Organs Is Associated With Increased Activation and Effector Function

by Faizah Alotaibi, Faizah Alotaibi, Mark Vincent, Wei-Ping Min, James Koropatnick, James Koropatnick, James Koropatnick
Published 2021-01-01

498 Downregulation of CD5 in CD8+ T tumour-infiltrating lymphocytes associates with increased level of activation and exhaustion

by Faizah Alotaibi, Mark Vincent, Weiping Min, James Koropatnick
Published 2020-11-01

Novel anti-cancer drug COTI-2 synergizes with therapeutic agents and does not induce resistance or exhibit cross-resistance in human cancer cell lines.

by Saman Maleki Vareki, Kowthar Y Salim, Wayne R Danter, James Koropatnick
Published 2018-01-01

Inhibition of BRCA2 and Thymidylate Synthase Creates Multidrug Sensitive Tumor Cells via the Induction of Combined “Complementary Lethality”

by Mateusz Rytelewski, Peter J Ferguson, Saman Maleki Vareki, Rene Figueredo, Mark Vincent, James Koropatnick
Published 2013-01-01

Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy

by Steven F. Gameiro, Farhad Ghasemi, John W. Barrett, James Koropatnick, Anthony C. Nichols, Joe S. Mymryk, Saman Maleki Vareki
Published 2018-10-01

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

by Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill
Published 2017-08-01

IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells.

by Saman Maleki Vareki, Di Chen, Christine Di Cresce, Peter J Ferguson, Rene Figueredo, Macarena Pampillo, Mateusz Rytelewski, Mark Vincent, Weiping Min, Xiufen Zheng, James Koropatnick
Published 2015-01-01

miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

by Meng Zhang, Dian Gao, Yanmei Shi, Yifan Wang, Rakesh Joshi, Qiongfang Yu, Daheng Liu, Faizah Alotaibi, Yujuan Zhang, Hongmei Wang, Qing Li, Zhu-Xu Zhang, James Koropatnick, Weiping Min
Published 2019-10-01

A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases

by Anthony C. Nichols, Michelle Chan-Seng-Yue, John Yoo, Sumit K. Agrawal, Maud H. W. Starmans, Daryl Waggott, Nicholas J. Harding, Samuel A. Dowthwaite, David A. Palma, Kevin Fung, Bret Wehrli, S. Danielle MacNeil, Philippe Lambin, Eric Winquist, James Koropatnick, Joe S. Mymryk, Paul C. Boutros, John W. Barrett
Published 2013-01-01