The role of B cells in systemic sclerosis

by Marina D Kraaij, Jacob M van Laar
Published 2008-09-01

Tweaking microtubules to treat scleroderma.

by Jacob M van Laar, Tom W J Huizinga
Published 2005-12-01

Differentiation potential of CD14+ monocytes into myofibroblasts in patients with systemic sclerosis.

by Nadine Binai, Steven O'Reilly, Bridget Griffiths, Jacob M van Laar, Thomas Hügle
Published 2012-01-01

MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-β activated kinase 1 binding protein 1, implications for systemic sclerosis.

by Marzena Ciechomska, Steven O'Reilly, Monika Suwara, Katarzyna Bogunia-Kubik, Jacob M van Laar
Published 2014-01-01

Changes in bone density and bone turnover in patients with rheumatoid arthritis treated with rituximab, results from an exploratory, prospective study.

by Gillian Wheater, Mohsen Elshahaly, Kamran Naraghi, Stephen P Tuck, Harish K Datta, Jacob M van Laar
Published 2018-01-01

Text Mining of Electronic Health Records Can Accurately Identify and Characterize Patients With Systemic Lupus Erythematosus

by Tammo E. Brunekreef, Henny G. Otten, Suzanne C. van denBosch, Imo E. Hoefer, Jacob M. vanLaar, Maarten Limper, Saskia Haitjema
Published 2021-02-01

Resetting the T Cell Compartment in Autoimmune Diseases With Autologous Hematopoietic Stem Cell Transplantation: An Update

by Lisanne Lutter, Julia Spierings, Femke C. C. van Rhijn-Brouwer, Femke C. C. van Rhijn-Brouwer, Jacob M. van Laar, Femke van Wijk
Published 2018-04-01

Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotre...

by Xavier M. Teitsma, Johannes W. G. Jacobs, Michal Mokry, Michelle E. A. Borm, Attila Pethö-Schramm, Jacob M. van Laar, Johannes W. J. Bijlsma, Floris P. J. Lafeber
Published 2017-07-01

Heat Shock Proteins Can Be Surrogate Autoantigens for Induction of Antigen Specific Therapeutic Tolerance in Rheumatoid Arthritis

by Willem van Eden, Manon A. A. Jansen, Manon A. A. Jansen, Irene S. Ludwig, Irene S. Ludwig, Paul Leufkens, Paul Leufkens, Marlies C. van der Goes, Jacob M. van Laar, Femke Broere, Femke Broere
Published 2019-02-01

Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combin...

by Xavier M Teitsma, Wei Yang, Johannes W G Jacobs, Attila Pethö-Schramm, Michelle E A Borm, Amy C Harms, Thomas Hankemeier, Jacob M van Laar, Johannes W J Bijlsma, Floris P J G Lafeber
Published 2018-10-01

Effectiveness of TOcilizumab in comparison to Prednisone In Rheumatoid Arthritis patients with insufficient response to disease-modifying antirheumatic drugs (TOPIRA): study protoc...

by Matthijs S. van der Leeuw, Paco M. J. Welsing, Maria J. H. de Hair, Johannes W. G. Jacobs, Anne C. A. Marijnissen, Suzanne P. Linn-Rasker, Faouzia Fodili, Reinhard Bos, Janneke Tekstra, Jacob M. van Laar
Published 2020-04-01

The multi-biomarker disease activity score tracks response to rituximab treatment in rheumatoid arthritis patients: a post hoc analysis of three cohort studies

by Nadia M. T. Roodenrijs, Maria J. H. de Hair, Gill Wheater, Mohsen Elshahaly, Janneke Tekstra, Y. K. Onno Teng, Floris P. J. G. Lafeber, Ching Chang Hwang, Xinyu Liu, Eric H. Sasso, Jacob M. van Laar
Published 2018-11-01

Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease

by Sadaf Atarod, Sadaf Atarod, Jean Norden, Louis A. Bibby, Anne Janin, Philippe Ratajczak, Clare Lendrem, Kim F. Pearce, Xiao-Nong Wang, Steven O’Reilly, Jacob M. Van Laar, Matthew Collin, Anne M. Dickinson, Rachel E. Crossland
Published 2018-07-01

Identification and prediction of difficult-to-treat rheumatoid arthritis patients in structured and unstructured routine care data: results from a hackathon

by Marianne A. Messelink, Nadia M. T. Roodenrijs, Bram van Es, Cornelia A. R. Hulsbergen-Veelken, Sebastiaan Jong, L. Malin Overmars, Leon C. Reteig, Sander C. Tan, Tjebbe Tauber, Jacob M. van Laar, Paco M. J. Welsing, Saskia Haitjema
Published 2021-07-01

Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study

by Sylvia J. Kroese, Carolien N. H. Abheiden, Birgit S. Blomjous, Jacob M. van Laar, Ronald W. H. M. Derksen, Irene E. M. Bultink, Alexandre E. Voskuyl, A. Titia Lely, Marjon A. de Boer, Johanna I. P. de Vries, Ruth D. E. Fritsch-Stork
Published 2017-01-01

Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis.

by Bart V J Cuppen, Junzeng Fu, Herman A van Wietmarschen, Amy C Harms, Slavik Koval, Anne C A Marijnissen, Judith J W Peeters, Johannes W J Bijlsma, Janneke Tekstra, Jacob M van Laar, Thomas Hankemeier, Floris P J G Lafeber, Jan van der Greef, all Society for Rheumatology Research Utrecht investigators
Published 2016-01-01

A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis: the UPSIDE study protocol

by Ellen De Langhe, Jacob M van Laar, Alexandre E Voskuyl, Madelon C Vonk, Roger Hesselstrand, Dirk M Wuttge, Reinhard E Voll, Arjan A van de Loosdrecht, Julia Spierings, Joerg Henes, Anna van Rhenen, Paco MW Welsing, Anne CA Marijnissen, Daan Dierickx, Karina R Gheorghe, Tessa Kerre, Erik WAF Marijt, Miro Mayer, Marc Schmalzing, Roland Schroers
Published 2021-03-01

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.

by F David Carmona, Jose-Ezequiel Martin, Lorenzo Beretta, Carmen P Simeón, Patricia E Carreira, José Luis Callejas, Mónica Fernández-Castro, Luis Sáez-Comet, Emma Beltrán, María Teresa Camps, María Victoria Egurbide, Spanish Scleroderma Group, Paolo Airó, Raffaella Scorza, Claudio Lunardi, Nicolas Hunzelmann, Gabriela Riemekasten, Torsten Witte, Alexander Kreuter, Jörg H W Distler, Rajan Madhok, Paul Shiels, Jacob M van Laar, Carmen Fonseca, Christopher Denton, Ariane Herrick, Jane Worthington, Annemie J Schuerwegh, Madelon C Vonk, Alexandre E Voskuyl, Timothy R D J Radstake, Javier Martín
Published 2013-01-01